40岁以上高龄妇女获卵数对体外受精-胚胎移植助孕结局的影响  

Impact of retrieved oocytes number on IVF-ET outcome in infertile women over 40 years of age

作　　者：彭玲[1,2] 储亚平[1] 魏兆莲[1] 许孝凤[1] 徐玉萍[1] 章志国[1] 

机构地区：[1]安徽医科大学第一附属医院妇产科生殖中心,合肥230022 [2]马鞍山市妇幼保健院妇产科,马鞍山243000

出　　处：《安徽医科大学学报》2017年第1期105-108,共4页Acta Universitatis Medicinalis Anhui

基　　金：国家科技支撑计划项目(编号:2012BAI32B00)

摘　　要：目的探讨获卵数对40岁以上高龄不孕妇女行体外受精-胚胎移植(IVF-ET)治疗后的助孕结局的影响。方法对行IVF-ET治疗的40岁以上高龄妇女的229个移植周期的临床资料进行回顾性分析。按获卵数分为3组,A组:获卵数<5个;B组:获卵数5~9个;C组:获卵数≥10个。分析3组IVF-ET治疗的妊娠结局。结果统计229个移植周期,48个周期获临床妊娠,23个周期获活产,临床妊娠率为20.9%,活产率为10.0%。A、B、C组的临床妊娠率分别为15.7%、23.0%、22.1%,活产率为5.9%、12.1%、10.6%。结论 40岁以上高龄不孕妇女IVF治疗活产率低,临床妊娠率以及活产率不随获卵数增多而增加。Objective To determine the influence of retrieved oocytes number on the outcome of in vitro fertilization and embryo transfer（IVF-ET） in the infertile women over 40 years of age. Methods A retrospective study of 229 cycles of IVF in the infertile women over 40 years of age performed. They were divided into three groups depending on retrieved oocytes number：A group： 〈5;B group：5 -9;C group： ≥10. Results There were 229 transplanting cycles. The clinical pregnancy rate was 20. 9% occured in 48 cycles, and the live birth rate was 10% occured in 23 cycles. The clinical pregnancy rates of A,B, C groups were 15.7% ,23.0% ,22. 1% , and the live birth rates were 5.9% ,12. 1% ,10. 6%. Conclusion The live birth rate in the advanced age infertile women is low,and there is no direct correlation between the number of oocytes retrieved and the clinical pregnancy rate and live birth rate.

关 键 词：体外受精-胚胎移植 高龄 卵子 获卵数 

分 类 号：R711.6[医药卫生—妇产科学]