不同负荷室性期前收缩与心脏结构及心功能的相关性研究  

Correlation among heart structure,cardiac function and premature ventricular systole of different loads

作　　者：宋晓坤[1] SONG Xiao-kun(Department of Ultrasound, Central Hospital of Dandong City, Dandong, Liaoning, 118002, China)

机构地区：[1]辽宁省丹东市中心医院超声科,辽宁丹东118002

出　　处：《心血管康复医学杂志》2017年第1期55-59,共5页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨不同负荷室性期前收缩与心脏结构及心功能的相关性。方法:选择我院收治的220例室性期前收缩患者,根据室性期前收缩数量与24h总心率的比值,分为低负荷组(<10%,50例)、中负荷组(10%~20%,108例)、高负荷组(>20%,62例),同时选择68例无室性期前收缩的体检者作为正常对照组,记录各组患者的心功能参数指标,同时检测其血清N末端脑钠肽(NT-proBNP)水平,并分析其相关性。结果:与正常对照组相比,中负荷组及高负荷组的QT间期、QRS波时限明显增宽,矫正QT间期明显延长(P<0.05或<0.01)。与正常对照组相比,中负荷组、高负荷组的左心房内径(LAD)、左心室流出道内径(LVOT)、左心室舒张末期内径(LVEDd)、右心室舒张末期内径(RVEDd)、左心室舒张末期容积(LVEDV)、每博心输出量(SV)、左心室心肌质量指数(LVMI)、NT-proBNP水平均明显升高,左室射血分数(LVEF)显著降低(P<0.05或<0.01)。双变量直线相关分析显示,室性期前收缩负荷与QRS波时限、矫正QT间期、LVEDd、RVEDd、NT-proBNP呈直线正相关(r=0.42~0.65,P均<0.01);与LVEF呈直线负相关(r=-0.62,P=0.001)。结论:随着室性期前收缩负荷的增加,左室的结构及功能可发生改变,因此应注意监测相关指标,及早进行临床干预。Objective： To explore correlation among le （PVS） of different loads,. Methods： A total of to PVS number-to-24h total heart rate ratio, they heart structure, cardiac function and premature ventricular systo- 220 PVS patients treated in our hospital were selected. According were divided into low load group （〈10%, n = 50）, medium load group （10% -20%, n = 108） and high load group （〉20%, n = 62）. Another 68 subjects without PVS were regarded as normal control group. Cardiac function indexes and serum level of N terminal pro brain natriuretic peptide （NT- proBNP） were measured in all groups, and their correlation was analyzed. Results： Compared with normal control group, there were significant rise in QT interval, QRS wave duration and corrected QT interval in medium and high load groups, P〈0.05 or 〈0.01. Compared with normal control group, there were significant rise in left atrial diameter （LAD）, left ventricularoutflow tract dimension （LVOT）, left ventricular end-diastolic dimension （LVEDd）, right ventricular end-diastolic stroke volume （SV）, left ventricular mass dimension （RVEDd）, left ventricular end-diastolic volume （LVEDV）, index （LVMI） and NT-proBNP level, and significant reduction in left ventricular ejection fraction （LVEF） in medium and high load group, P〈0.05 or 〈0.01. Bivariate linear correla- tion analysis indicated that PVS load was significant linear positively correlated with QRS wave duration, corrected QT interval, LVEDd, RVEDd and NT-proBNP level （r = 0. 42-0. 65, P〈0.01 all） ; and significant linear inversely correlated with LVEF （ r = - 0.62, P = 0. 001）. Conclusion： Changes may occur in left ventricular structure and function along with PVS load rises. Therefore, attention should be paid on monitoring related indexes in order to perform early intervention.

关 键 词：室性早搏复合征 心电描记术 便携式 超声心动描记术 多普勒 心室功能 

分 类 号：R541.709[医药卫生—心血管疾病]