右美托咪定在老年心房颤动患者麻醉中的应用效果分析  

Clinical effect analysis of using dexmedetomidine on anesthesia in senile atrial fibrillation patients

作　　者：钟巍[1] 苏孟勤[1] 任苏恩[1] 韩雪萍[2] 

机构地区：[1]河南省胸科医院,郑州450052 [2]郑州大学第一附属医院,郑州450052

出　　处：《北方药学》2017年第1期17-18,共2页Journal of North Pharmacy

摘　　要：目的:探讨右美托咪定在老年心房颤动患者麻醉中的应用效果分析。方法:选取2015年6月~2016年6月我院收治的88例老年心房颤动患者,按照随机数字表法分为观察组和对照组,每组44例,对照组给予常规麻醉,观察组在对照组基础上于麻醉诱导前给予右美托咪定,比较两组麻醉效果。结果:两组T1~T3时间段SBP、DBP均显著高于T0时刻(均P<0.05),HR、BIS均显著低于T0时刻(均P<0.05),观察组T1~T3时间段SBP、DBP均显著高于对照组时刻(均P<0.05),HR、BIS均显著低于对照组(均P<0.05)。观察组呼吸恢复、呼唤睁眼:定向力恢复时间均显著短于对照组(均P<0.05)。观察组低血压、心动过速的发生率分别为4.54%、2.27%显著低于对照组的25.0%、18.18%(均P<0.05),观察组高血压、心动过缓发生率低于对照组,但无显著差异(均P>0.05)。结论:右美托咪定辅助麻醉可稳定老年心房颤动患者麻醉过程中血流动力学指标,缩短麻醉恢复时间,降低心血管不良事件发生率,值得临床推广。Objective：To investigate the curative effects of using dexmedetomidine on the anesthesia in senile atrial fibrillation patients.Methods：From June 2015 to June 2016 in our hospital 88 cases of senile atrial fibrillation patients were selected and randomly divided into the observation group and the control group（44 cases in each group）; The control group were given routine anesthesia,while the observation group had dexmedetomidine on the basis of the control group before anesthesia induction. The anesthetic effects in the two groups were compared. Results：In the two groups of patients at T1~T3 time segment SBP and DBP were significantly higher than those at T0（all P〈0.05）,while HR and BIS were significantly lower than those at T0 moment（all P〈0.05）; And in the observation group at T1~T3 time SBP and DBP were significantly higher than those in the control group（all P〈0.05）,while HR and BIS were significantly lower than those in the control group（all P〈0.05）. In the observation group breathing,calling eye opening orientation recovery time were significantly shorter than those in the control group（all P〈0.05）. In the observation group the incidences of hypotension and tachycardia occurred were 4.54% and 2.27% repectively,significantly lower than those in the control group 25% and 18.18%（all P〈0.05）; The incidences of hypertension and bradycardia in the observation group were lower than those in the control group,but without significant difference（P〉0.05）. Conclusion：Using dexmedetomidine assisted anesthesia hemodynamics during anesthesia in senile atrial fibrillation patients could shorten the anesthesia recovery time and reduce the adverse cardiovascular event rate,worthy of clinical promotion.

关 键 词：右美托咪定 老年心房颤动 麻醉 

分 类 号：R614[医药卫生—麻醉学]