对甲苯磺酸与碘协同催化合成月桂酸甲酯  

Synthesis of Methyl Laurate Catalyzed by Concerted Catalysis of TsOH Cooperate with I_2

作　　者：王琳琳[1] 杜莹[1] 吴小云[1] 罗世霞[1] 尹晓刚[1] WANG Lin-lin DU Ying WU Xiao-yun LUO Shi-xia YIN Xiao-gang(Key Eaboratory of Functional Materials Chemistry of Guizhou Province, School of Chemistry and Materials Science, Guizhou Normal University, Guiyang 550001, China)

机构地区：[1]贵州师范大学化学与材料科学学院贵州省功能材料化学重点实验室,贵州贵阳550001

出　　处：《合成化学》2017年第2期144-147,共4页Chinese Journal of Synthetic Chemistry

基　　金：国家自然科学基金资助项目(21362006);贵州省科技合作项目(黔科合LH字[2016]7218);贵州省科技厅科技支撑项目(黔科合支撑[2016]2311)

摘　　要：以甲醇(1)和月桂酸(2)为原料,碘和对甲苯磺酸协同催化合成了月桂酸甲酯(3),其结构经IR确证。考察了催化剂、反应时间、反应温度和物料比r[n(1)∶n(2)]对3产率的影响。结果表明:在最优反应条件(2 10mmol,r=15∶1,3 mol%TsOH,6 mol%I2,于60℃反应90 min)下,3产率93.5%。Methyl laurate （3） was synthesized using MeOH （ 1 ） and lauric acid （2） as the materials and TsOH-I2 as the cooperative catalyst. The structure was confirmed by IR. Effects of catalysts, reaction time, temperature and material mole ratio [ r = n （ 1 ） ： n （2） ] on yield of 3 were investigated. The results indicated that under the optimum reaction conditions（2 10mmol, r = 15 ： 1, 3 mol%TsOH, 6mol% I2, reaction at 60 ℃ for 90 min）, the yield of 3 was 93.5%.

关 键 词：月桂酸甲酯 对甲苯磺酸 碘 协同催化 合成 

分 类 号：O621.3[理学—有机化学]