河北廊坊地区黄褐斑流行病学调查  

Prevalence of chloasma among community residents in Langfang region of Hebei province

作　　者：周娜娜[1] 景伟芳[1] 刘雪[1] 魏艳丽[1] 孟雪梅[1] 王婷琳[2] 彭光辉[2] 张建中[2] 

机构地区：[1]中国石油天然气集团公司中心医院皮肤科,河北廊坊065000 [2]北京大学人民医院皮肤科

出　　处：《中国公共卫生》2017年第2期229-232,共4页Chinese Journal of Public Health

摘　　要：目的探讨河北省廊坊地区黄褐斑患病率及其影响因素。方法于2013年3—5月在河北省廊坊地区采用整群抽样调查方法对4个社区居民进行流行病学调查。结果共调查3 596人,黄褐斑患者124例,总患病率为3.4%,标化患病率为4.3%。其中,男性患病率为0.3%(5/1 891),女性患病率为7.0%(119/1 705),女性高于男性(P<0.05);已婚/离异/丧偶者患病率最高为5.4%(117/2 176);职业以科研人员患病率最高为10.8%(50/463);中学/中专及以上文化程度者患病率高于小学及以下者;性格内向、抑郁者患病率最高为8.8%(19/217),性格平和者最低为2.7%(63/2 323);生活感觉很疲惫者患病率最高为7.2%(43/594),较轻松者患病率最低为1.4%(14/1 034);喜好油腻、辛辣及甜食者患病率为4.0%(94/2 346),非喜好者患病率为2.5%(30/1 215)。多因素非条件logistic回归分析结果显示,女性、年龄30~59岁、已婚、内向抑郁性格和生活压力一般、疲劳为黄褐斑患病的危险因素,职业为退体和其他为黄褐斑患病的保护因素。结论性别、年龄、婚姻状况、性格、职业和生活压力是黄褐斑患病的主要影响因素。Objective To explore the prevalence and influencing factors of chloasma among residents in Langfang region. Methods We conducted a household survey including questionnaire interview and skin examination among 3 596 residents recruited from four communities in Langfang region of Hebei province, China with cluster random sampling between March and May 2013. Results Of all the participants, 124 were detected with chloasma, with an overall prevalence of 3.4% and a standardized prevalence of 4. 3 %. The prevalence of cholsma differed by gender, marital status, occupation, education level,personality, life stress, and dietary behaviors, with higher prevalences among the females than the males （7.0% vs. 0. 3% ,P 〈0. 05） ,the scientific research personnel （ 10. 8% ,50/463） than other occupations （P 〈 0. 05 ）, the participants with the education of technical secondary school or above than with lower education, the participants with introvert personality or depression symptoms （8. 8%, 19/217 ） than with calm personality （ 2. 7%, 63/ 2 323） ,the participants with heavy perceived life stress （7.2% ,43/594） than with minor perceived life stress （1.4% , 14/1 034）,and the participants with preference for greasy,spicy and sweet food （4. 0% ,94/2 346） than without the preference （2. 5% ,30/1 215）, respectively. The results of logistic regression analysis demonstrated that female gender （ odds ratio[ OR] = 23. 203, P 〈 0. 001 ）, married （ OR = 17. 265, P 〈 0. 001 ）, introvert personality or depression symp- toms （ OR = 3. 261 ,P 〈 0. 001 ） ,preference for greasy, spicy and sweet food （ OR = 1. 557, P = 0. 054 ）, and heavy perceived life stress （ OR = 1.529, P = 0. 006） were risk factors for chloasma; whereas age was a protective factor for chloasma （ OR = 0. 808,P = 0. 034）. Conclusion Gender age, marital status, personality, occupation, and life stress are main influencing factors of chlosma among community residents in Langfang.

关 键 词：黄褐斑 流行病学调查 影响因素 廊坊 

分 类 号：R758[医药卫生—皮肤病学与性病学]