系统性红斑狼疮患者医院感染危险因素分析及干预对策  

Analysis of clinical risk factors and intervention countermeasures of nosocomial infections in patients with systemic lupus erythematosus

作　　者：施善芬[1] 黎良达[1] 单爱琴[1] 何永平[1] 张飞[2] 

机构地区：[1]宁波大学附属鄞州人民医院风湿免疫科,浙江宁波315040 [2]浙江省人民医院内科,浙江杭州310006

出　　处：《中华医院感染学杂志》2017年第3期583-585,共3页Chinese Journal of Nosocomiology

基　　金：浙江省医药卫生科技计划基金资助项目(2013MHJ122)

摘　　要：目的探讨系统性红斑狼疮患者发生医院感染的临床危险因素并提出干预对策。方法选择2011年1月-2016年1月医院接诊98例系统性红斑狼疮患者,观察其医院感染率,分析临床危险因素,并提出干预对策。结果 98例患者中有40例患者发生感染,感染率为40.81%,感染部位主要为呼吸道占35.00%;引起感染的危险因素中,年龄、狼疮涉及脏器、C-反应蛋白、血清白蛋白、激素用量、免疫抑制剂、体温、住院时间、白细胞均具有显著关系(P<0.05)。结论引起系统性红斑狼疮患者发生医院感染的危险因素较多,在临床上应给予相应针对性的干预对策,在降低感染率、提高预后上具有积极意义。OBJECTIVE To investigate the clinical risk factors of nosocomial infections in patients with systemic lupus erythematosus and puts forward the intervention countermeasures.METHODS A total of 98 cases of patients with systemic lupus erythematosus from Jan.2011 to Jan.2016 in hospital were selected.The incidence of infections in hospital was observed,the clinical risk factors were analyzed,and the countermeasures were put forward.RESULTS In 98 patients,40patients had infections,with the infection rate of 40.81%.Infections occurred mainly in the respiratory tract,and the proportion was 35.00%（14/40）.Among the risk factors of infections,the age,lupus related organs,C-reactive protein,serum albumin,hormone dosage,immune inhibitors,body temperature,length of stay,and white blood cells were significantly related（P〈0.05）.CONCLUSIONThere are many risk factors of nosocomial infections in patients with systemic lupus erythematosus,and the corresponding clinical intervention countermeasure should be given to reduce the infection rate and improve the prognosis.

关 键 词：系统性红斑狼疮 医院感染 危险因素 干预对策 

分 类 号：R181.32[医药卫生—流行病学]