miRNA与热应激的关系及检测方法进展  

Development of detection methods and relationship between miRNA and heat stress

作　　者：郭文晋[1] 连帅[1] 李悦[1] 翟骏飞 张宇辰[1] 郭景茹[1] 计红[1] 甄莉[1] 杨焕民[1] GUO Wen-jin LIAN Shuai LI Yue ZHAI Jun-fei ZHANG Yu-chen GUO Jing-ru JI Hong ZHEN Li YANG Huan-min(College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing Heilongjiang 163000, China)

机构地区：[1]黑龙江八一农垦大学动物科技学院,黑龙江大庆163000

出　　处：《中国实验动物学报》2016年第6期666-669,共4页Acta Laboratorium Animalis Scientia Sinica

基　　金：国家自然基金项目资助(批准号:31372398);教育部博士点导师基金(编号:20132305110004);黑龙江省自然科学基金面上项目(C2015041);黑龙江省教育厅重点实验室开放课题(AMKL201302)

摘　　要：热应激是机体长期暴露在热环境中无法充分将体内的热散出而导致机体温度失衡的一种状态。随着miRNA检测技术的进步,许多学者发现,热应激会导致miRNA的表达量发生变化。miRNA可以通过结合其靶基因,抑制miRNA靶基因的表达,从而在调控机体生命活动和抗热应激中发挥重要作用。Heat stress which leads to a state of temperature imbalance caused by long-term exposure of the body in a thermal environment and the body could not adequately dissipate heat. With the progress of the miRNA measurement technology,many scholars had found that heat stress can lead to a change in the miRNA. expression miRNA can bind its target genes to inhibit the expression of its target genes. That made miRNA to play an important role in the regulation of the body＇s life activities and anti-heat stress.

关 键 词：热应激 MIRNA 靶基因 抗热应激 

分 类 号：Q95-33[生物学—动物学]