Rhodium（lll）/Amine Synergistically Catalyzed Enantioselective Alkylation of Aldehydes with α,β-Unsaturated 2-Acyl Imidazoles  

作　　者：Jun Gong Kuan Li Saira Qurban Qiang Kang 

机构地区：[1]Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China [2]Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China

出　　处：《Chinese Journal of Chemistry》2016年第12期1225-1235,共11页中国化学（英文版）

摘　　要：A synergistic catalysis combination of chiral-at-metal rhodium complex and amine catalyst was developed for enantioselective alkylation of aldehydes with α,β-unsaturated 2-acyl imidazoles. The corresponding adducts were obtained in good yields with excellent enantioselectivities （up to 99% ee）.A synergistic catalysis combination of chiral-at-metal rhodium complex and amine catalyst was developed for enantioselective alkylation of aldehydes with α,β-unsaturated 2-acyl imidazoles. The corresponding adducts were obtained in good yields with excellent enantioselectivities （up to 99% ee）.

关 键 词：alkylation of aldehyde chiral-at-metal complex synergistic catalysis 

分 类 号：O623.425[理学—有机化学] Q965[理学—化学]