2011～2015年北京大学第三医院成人住院患者营养药品应用调查  

A Comprehensive Survey of the Utilization of Nutrition Preparations in Adult Inpatient in Peking University Third Hospital during 2011-2015

作　　者：李潇潇[1,2] 葛庆岗[1,3] 伊敏[1,3] 么改琦[1,3] 翟所迪[2] 

机构地区：[1]北京大学第三医院营养支持小组,北京100191 [2]北京大学第三医院药剂科,北京100191 [3]北京大学第三医院危重医学科,北京100191

出　　处：《药物流行病学杂志》2017年第2期133-136,142,共5页Chinese Journal of Pharmacoepidemiology

基　　金：卫生部临床重点专科建设项目(编号:56495-04);北京市科技计划首都特色应用研究(编号:Z141107002514020;Z151100004015135)

摘　　要：目的:调查北京大学第三医院成人住院患者营养药品的临床使用情况。方法:回顾性分析2011~2015年全院住院患者营养药品的使用率、使用结构变化,应用营养药品患者的疾病分布。结果:2011~2015年,住院患者的营养药品占住院药品总金额的比例维持稳定,肠外营养(PN)药品约占2.56%,肠内营养(EN)药品约占1.79%。PN用药人数占同期出院人数的比例自5.90%上升至6.31%,EN用药自1.53%上升至2.15%。PN药品的人均日用量自0.16瓶(袋)上升至0.23瓶(袋)。其中配置全合一三升袋占PN总使用人次的比例自6.55%上升至13.66%,多腔袋自28.84%增至36.58%,单瓶输注现象同比下降,降幅达36.11%。EN人均日用量稳定波动于0.11~0.13瓶(袋)。消化道恶性肿瘤、肠梗阻、梗阻性黄疸、血液肿瘤、急性胰腺炎等是PN的主要患者人群。脑血管疾病、呼吸衰竭、呼吸系统感染以及运动神经元病变等是使用EN的主要患者人群。结论:近5年我院营养药品的使用率逐步提高,不同类型营养制剂的结构变化表明临床选择基本合理。使用营养药品的患者人群符合指南推荐,并有我院特色。未来需进一步提高肠内营养制剂的使用率。Objective： To investigate the clinical use of nutrition preparation in adult inpatient in Peking University Third Hospital. Methods：A retrospective study was conducted to analyze the utilization rate, constitute change and disease distribution of nutrition preparation in inpatient during 2011-2015. Results：The proportion, expressing asconsumption sum of nutrition preparation in total drug income from inpatients, was stable during 2011-2015. It was 2.56% for parenteral nutrition （PN） and 1.79% for enteral nutrition （EN）. Inpatients prescribed PN preparation in total concurrent discharged inpatients increased from 5.90% to 6.31% for PN, and from 1.53% to 2.15% for EN. The personal daily consumption of PN preparation increased from 0.16 bottle （bag） to 0.23 bottle （bag）. The proportion of total nutrition admixtures and multiple-compartment bag in PN preparation was 6.55% and 28.84% in 2011, and rose up to 13.66% and 36.58% in 2015, respectively, meanwhile, single bottle infusion made a 36.11% drop. The personal daily consumption of EN preparations fluctuated between 0.11 and 0.13 bottle （bag）, which was stable. The primary diseases in patients using PN preparation were gastrointestinal malignancies, ileus, obstruction jaundice, hematologic neoplasms and acute pancreatitis. Cerebrovascular disease, respiratory failure or infection, along with motor neuron disease was the most common diseases in patients using EN preparation. Conclusion：The utilization rate of nutrition preparation in inpatients improved gradually in the last five years, and the constitute change of it suggested a rational use. The disease distribution showed clinical use complied with guidelines and had a unique feature of the hospital. The utilization of EN should be improved in future.

关 键 词：肠外营养 肠内营养 住院患者 药物利用 

分 类 号：R977[医药卫生—药品]