一清胶囊联合重组人干扰素α2b治疗病毒性结膜炎的疗效观察  

Clinical observation of Yiqing Capsules combined with interferon in the treatment of viral conjunctivitis

作　　者：何琎 张炯 

机构地区：[1]苏州明基医院眼科,江苏苏州215000

出　　处：《现代药物与临床》2017年第1期113-115,共3页Drugs & Clinic

摘　　要：目的探讨一清胶囊联合重组人干扰素α2b治疗病毒性结膜炎的临床疗效。方法选取2014年5月—2015年12月苏州明基医院收治的病毒性结膜炎患者83例,随机分为对照组(41例)与治疗组(42例)。对照组患者肌肉注射重组人干扰素α2b注射液,300万U/次,1次/d。治疗组者在对照组的基础上口服一清胶囊,1 g/次,3次/d。两组患者均连续治疗14 d。观察比较两组患者治疗后临床疗效、疼痛消失时间、畏光流泪消失时间、平均治愈时间。结果治疗后,对照组患者总有效率为90.24%,显著低于治疗组的100.00%,两组比较差异具有统计学意义(P<0.05)。治疗后,治疗组患者疼痛消失时间、畏光流泪消失时间及平均治愈时间均显著短于治疗后对照组,两组比较差异具有统计学意义(P<0.05)。结论一清胶囊联合重组人干扰素α2b治疗病毒性结膜炎疗效显著,能缩短治疗时间,具有一定的临床推广应用价值。Objective To explore the clinical efficacy of Yiqing Capsules combined with interferon in the treatment of viral conjunctivitis. Methods Patients （83 cases） with viral conjunctivitis in Suzhou BenQ Hospital from May 2014 to December 2015 were randomly divided into control （41 cases） and treatment （42 cases） groups. Patients in the control group were im administered with Recombinant Human Interferon α2b Injection, 3 million U/time, once daily. Patients in the treatment group were po administered with Yiqing Capsules on the basis of the control group, 1 g/time, three times daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacy, the disappearing time of pain and phengophobia tears, and the average healing time in two groups were compared. Results After treatment, the clinical efficacy in the control group was 90.24%, which was significantly lower than that （100.00%） of the treatment group, and there were differences between two groups （P 〈 0.05）. After treatment, the disappearing time of pain and phengophobia tears, and the average healing time in the treatment group were significantly shorter than those in the control group, with significant difference between two groups （P 〈 0.05）. Conclusion Yiqing Capsules combined with interferon has a significant effect in the treatment of viral conjunctivitis, can shorten the therapy time, which has a certain clinical application value.

关 键 词：一清胶囊 重组人干扰素α2b注射液 病毒性结膜炎 临床疗效 治愈时间 

分 类 号：R988.1[医药卫生—药品]