正交试验优化厚朴七物汤水提取工艺  

Extraction technology of Houpu Qiwu decoction

作　　者：张文娓[1] 王一[1] 方芳[1] 田明[1] ZHANG Wen-wei WANG Yi FANG Fang TIAN Ming(Teaching Laboratory Center, Heilongiiang University of Chinese Medicine, Harbin 150040, China)

机构地区：[1]黑龙江中医药大学教学实验中心,哈尔滨150040

出　　处：《哈尔滨商业大学学报（自然科学版）》2016年第4期421-425,共5页Journal of Harbin University of Commerce：Natural Sciences Edition

摘　　要：为优选厚朴七物汤水提取工艺,采用正交试验法设计水提取工艺,以出膏率、含浸出物百分量和厚朴酚与和厚朴酚,及含大黄总蒽醌量为测定指标,考察加水量,提取次数和回流时间三个因素参数,确定最佳提取工艺条件.结果表明,厚朴七物汤最佳提取工艺为回流提取3次,第一次加水10倍量提取1.5 h,第二次加水8倍量提取1.0 h,第三次加水6倍量提取0.5 h.厚朴七物汤的水提取工艺简便易行,效率高,稳定可行.To study the optimal extraction process of Houpu Qiwu decoction,the orthogonal experiment was used. The optimal extraction process was determined with the rate of extraction,the percentage composition of extractive and the content of magnolol,honokil and total anthraquinone in radix et rhizoma rhei as the index. Results indicated that the optimal extraction of Houpu Qiwu decoction was reflux extraction 3 times,the first time of 1. 5 h with10 times water; the second time of 1 h with 8 times water,and the third time of 0. 5 h with6 times water. The optimal extraction technology was easy,high efficiency and stable.

关 键 词：厚朴七物汤 提取工艺 厚朴酚 和厚朴酚 大黄总蒽醌 

分 类 号：R284[医药卫生—中药学]