口服缓释制剂的研究进展  

The research situation of sustained-release formulation

作　　者：杨萍[1] 全姬善[1] 

机构地区：[1]延边大学药学院,吉林延吉133000

出　　处：《药学研究》2017年第1期44-47,共4页Journal of Pharmaceutical Research

摘　　要：缓释制剂作为一种前沿的药物剂型在制药行业得到广泛的研究和应用。缓释制剂具有释药平稳、药效持久、副作用小等优点,不仅可以有效控制血药浓度,减少用药副反应,而且可以大大延长药物作用时间,减少服药次数,提高患者的顺应性,在药品实际生产应用中占据重要地位。目前,缓释制剂多用于传统药物的剂型改进和新药的开发。本文通过查阅相关文献,综述了口服缓释制剂的应用研究进展。Sustained-release formulation（SRP） as a forefront type of pharmaceutical preparations has been widely studied and applied.SRP has an important role in applications because of their sustained drug release,long-lasting efficacy and less side effects.SRP shows great efficacies in prolonging the drug retention time,decreasing the frequency of medication and enhancing patients compliance.At present,the sustained-release preparations were used to improve traditional medicine dosage forms and develop new drugs.After a review of the related literatures,this essay summarized the research and application progress of sustained-release preparations.

关 键 词：肠溶高分子材料 缓释制剂 胃内滞留系统 

分 类 号：R944.9[医药卫生—药剂学]