冬季发病与夏季发病的类风湿关节炎临床表现异同的研究  

On the Clinical Similarities and Differences Between the Onset of Rheumatoid Arthritis in Winter and Summer

作　　者：李院魏 张子扬[1,2] 娄玉钤 

机构地区：[1]河南风湿病医院,河南风湿病研究所,河南郑州450045 [2]河南中医药大学,河南郑州450046

出　　处：《风湿病与关节炎》2017年第2期22-25,共4页Rheumatism and Arthritis

基　　金：国家中医药管理局2014年全国名老中医药专家娄多峰传承工作室建设项目(国中医药人教发〔2014〕20号)

摘　　要：目的:探讨冬季发病与夏季发病的类风湿关节炎临床表现的异同,明确不同发病季节对中医辨证的意义。方法:将河南风湿病医院类风湿关节炎数据库(HFRA数据库)中收录的409例患者按发病季节分为冬季组和夏季组,并采用SPSS 19.0软件分析2组在关节表现及关节外表现方面的区别与联系。结果:通过对2组173个关节表现及关节外表现进行χ2检验,2组间差异有统计学意义的临床表现共6个,其中疼痛部位2个、关节受限部位2个、疼痛性质1个、关节外表现1个,通过对这6个临床表现进行证候分析可知,其相互之间无明显相关性。结论:冬季发病与夏季发病的类风湿关节炎临床表现无明显差异,不能作为中医辨证依据。Objective：To investigate the clinical manifestations of the onset of rheumatoid arthritis （ RA ） in winter and summer and clarify the significance of different onset seasons to TCM syndrome differentiation.Methods：Four hundred and nine cases with RA recorded in the HFRA database （ database of Henan Rheumatism Hospital ） were divided into a winter group and a summer group.The software SPSS 19.0 was used to analyze the differences and relations of articular and extra-articular manifestations of the two groups. Results：By Z2 test for the articular and extra-articular manifestations of 173 joints in the two groups,there were six of the manifestations being statistically significant,i.e.two painful parts,two joint limits,one painful property and one extra-articular manifestation.Symptom analysis showed that the six manifestations had no obvious correlation with each other.Conclusion：There is no significant difference between the onset of RA in winter and summer,which is not available for TCM syndrome differentiation.

关 键 词：类风湿 关节炎 夏季发病 冬季发病 临床表现 HFRA数据库 中医辨证 临床研究 

分 类 号：R593.22[医药卫生—内科学]