植物药活性成分环阿屯醇药理、生理活性及其研究展望  

Research advance of functional plant pharmaceutical cycloartenol about pharmacological and physiological activity

作　　者：张忠廉[1] 罗祖良[1] 石宏武[1] 张丽霞[1,2] 马小军[1,2] ZHANG Zhong-lian LUO Zu-liang SHI Hong-wu ZHANG Li-xia MA Xiao-jun(Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences ＆ Peking Union Medical College, Beijing 100193, China Yunnan Branch of Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences ＆ Peking Union Medical College, Jinghong 666100, China)

机构地区：[1]中国医学科学院北京协和医学院药用植物研究所,北京100193 [2]中国医学科学院北京协和医学院药用植物研究所云南分所,云南景洪666100

出　　处：《中国中药杂志》2017年第3期433-437,共5页China Journal of Chinese Materia Medica

基　　金：2015年公益性科研专项项目"中药饮片质量保障体系研究(一)"(201507002);中央级公益性科研院所基本科研业务专项(YZYN-15-05);国家自然科学基金面上项目(81373914)

摘　　要：环阿屯醇为植物甾醇类化合物,也是诸多甾醇类化合物生物合成的关键前体物质之一,具有抗炎、抗肿瘤、抗氧化、抗菌、抗阿尔兹海默症等多种活性,且在植物的生长发育过程中扮演重要角色。该文综述了国内外文献关于环阿屯醇药理活性的研究进展,并对环阿屯醇及"环阿屯醇途径"中甾醇类化合物对植物生长发育的影响进行概述,以为其进一步研究与开发应用奠定基础。Cycloartenol,a phytosterol compound,also one of the key precusor substances for biosynthesis of numerous sterol compounds,has a variety of pharmacological activities such as anti-inflammatory,anti-tumor,antioxidant,antibiosis and anti-alzheimer＇ s disease. Furthermore,cycloartenol also plays an important role in the process of plant growth and development. This article reviewed the research progress on cycloartenol pharmacological activity in domestic and foreign articles,and summarized the effect of cycloartenol and ＂ cycloartenol pathway ＂ on the plant growth and development,laying foundation for the its further study,development and utilization.

关 键 词：环阿屯醇 药理活性 生理活性 综述 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]