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出 处:《Bulletin of the Chinese Academy of Sciences》2016年第4期252-252,共1页中国科学院院刊(英文版)
摘 要:Human diseases may be caused by the malfunction of an intact protein.Hydrogen bond(h-bond)is one of the key interactions in maintaining the structure of a protein and facilitating its function.The presence and extent of h-bond cooperativity in proteins remains a fundamental question,and quantitativeHuman diseases may be caused by the malfunction of an intact protein.Hydrogen bond(h-bond)is one of the key interactions in maintaining the structure of a protein and facilitating its function.The presence and extent of h-bond cooperativity in proteins remains a fundamental question,and quantitative analysis of h-bond cooperativity is still lacking.
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