肾康注射液治疗慢性肾功能衰竭临床疗效观察  

Observation on clinical effect of Shenkang injection in the treatment of chronic renal failure

作　　者：李在楠[1] 王彩虹[1] 杨斌[2] 

机构地区：[1]内蒙古赤峰市医院肾内科,024000 [2]内蒙古赤峰市医院心内科

出　　处：《中国实用医药》2016年第36期125-126,共2页China Practical Medicine

摘　　要：目的探讨分析肾康注射液治疗慢性肾功能衰竭的临床效果,为慢性肾功能衰竭患者的治疗提供科学支持和理论指导。方法 120例慢性肾功能衰竭患者,随机分为对照组和实验组,每组60例。对照组患者给予常规治疗,实验组患者在此基础上给予肾康注射液治疗。记录两组患者治疗前后的血肌酐(Scr)、尿素氮(BUN)以及内生肌酐清除率(Ccr)的变化情况。结果治疗前实验组患者Scr为(448.98±62.98)μmol/L,BUN为(22.68±2.96)mmol/L,Ccr为(32.81±6.42)ml/min;治疗后Scr为(389.09±54.82)μmol/L,BUN为(16.09±5.15)mmol/L,Ccr为(38.14±6.55)ml/min。治疗前对照组Scr为(442.25±67.33)μmol/L,BUN为(22.86±2.90)mmol/L,Ccr为(33.33±5.30)ml/min;治疗后Scr为(421.42±62.56)μmol/L,BUN为(18.57±4.15)mmol/L,Ccr为(36.11±7.27)ml/min。治疗前两组Scr、BUN、Ccr比较差异均无统计学意义(P>0.05);治疗后两组Scr、BUN、Ccr均较治疗前改善,且实验组优于对照组,比较差异均具有统计学意义(P<0.05)。结论肾康注射液治疗慢性肾功能衰竭临床效果理想,值得临床推广。Objective To explore and analyze clinical effect of Shenkang injection in the treatment of chronic renal failure, to provide scientific support and theoretical guidance for the treatment of chronic renal failure. Methods A total of 120 chronic renal failure patients were randomly divided into control group and experimental group, with 60 cases in each group. The control group received conventional therapy, and the experimental group also received Shenkang injection for treatment. Record were made on serum creatinine （Scr）, urea nitrogen （BUN） and endogenous creatinine clearance rate （Ccr） before and after treatment in two groups. Results The experimental group had Set as （448.98 ± 62.98）μmol/L, BUN as （22.68 ± 2.96）mmol/L, Ccr as （32.81 ± 6.42）ml/min before treatment, and Scr as （389.09 ± 54.82）μmol/L, BUN as （16.09 ± 5.15）mmol/L, Ccr as （38.14 ± 6.55）ml/min after treatment. The control group had Scr as （442.25 ± 67.33）μmol/L, BUN as （22.86 ± 2.90） mmol/L, Ccr as （33.33 ± 5.30）ml/min before treatment and Scr as （421.42 ± 62.56）μmol/L, BUN as （18.57 ± 4.15） mmol/L, Ccr as （36.11 ± 7.27）ml/min after treatment. The difference of Scr, BUN and Ccr before treatment had no statistical significance in two groups （P〉0.05）; Both groups had better Scr, BUN and Ccr after treatment than those before treatment, and the experimental group was better than the control group. Their differences had statistical significance （P〈0.05）. Conclusion Shenkang injection shows perfect effect in the treatment of chronic renal failure, and it is worth clinical popularization.

关 键 词：肾康注射液 慢性肾功能衰竭 临床疗效 

分 类 号：R277.5[医药卫生—中医学]