LVIS支架辅助栓塞治疗颅内动脉瘤20例的临床分析  

LVIS stent-assisted embolization for treating intracranial aneurysm:a clinical analysis of 20 cases

作　　者：盛斌[1] 方兴根[1] 李真保[1] 吴德刚[1] 赖年升[1] 赵心同[1] 刘佳强[1] 徐善水[1] 

机构地区：[1]皖南医学院附属弋矶山医院神经外科,芜湖安徽241001

出　　处：《国际神经病学神经外科学杂志》2016年第6期551-554,共4页Journal of International Neurology and Neurosurgery

摘　　要：目的探讨LVIS支架辅助栓塞颅内动脉瘤的安全性及有效性。方法选取应用LVIS支架辅助栓塞治疗20例患者的颅内动脉瘤20个。并对其临床资料、血管内治疗方法及效果进行回顾性分析，根据Raymond分级评价动脉瘤栓塞程度，改良Rankin量表（modified Rankin Scale，mRS）评估其预后效果。结果所有患者支架释放满意。术后即刻造影见Raymond分级I级栓塞15例（75％），Ⅱ级栓塞4例（20％），Ⅲ级栓塞1例（5％）。经术后3-12月随访的18个动脉瘤中，均未见复发，其中16个动脉瘤影像学治愈（88．9％），2个瘤颈残留但稳定（11．1％）。在访的18位患者中15位预后良好（mRS：0-2分）。结论LVIS支架辅助弹簧圈栓塞安全可行，可提高动脉瘤的栓塞率和降低复发率，远期临床效果还有待大样本随访和临床经验的总结。Objective To investigate the safety and efficacy of low-profile visualized intraluminal support （LVIS） stent-assisted embo- lization in the treatment of intraeranial aneurysm. Methods A retrospective analysis was performed on the clinical data, endovaseular treatment methods, and clinical outcome of 20 patients with 20 intraeranial aneurysms who were treated with LVIS stent-assisted embo- lization. The degree of aneurysm embolization was evaluated according to the Raymond classification, and the clinical outcome was e- valuated using the modified Rankin Scale （mRS）. Results The stent release was satisfactory in all patients. Immediate postoperative angiography showed that Raymond grade I embolization was achieved in 15 patients （75%）, Raymond grade Ⅱ embolization in 4 pa- tients （20%）, and Raymond grade Ⅲ emholization in 1 patient （5%）. After 3 - 12 months of follow-up for 18 aneurysms, no recur- rence was observed; the imaging results showed that 16 （88.9%） of the 18 aneurysms were cured and 2 （ 11.1% ） remained stable. And 15 of the 18 patients had a good clinical outcome （mRS score 0 -2）. Conclusions LVIS stent-assisted coil embolization is safe and feasible. It can improve the embolization rate and reduce the recurrence rate of aneurysms. However, the long-term clinical effect needs to be confirmed by further studies with a large sample size and a summary of clinical experiences.

关 键 词：LVIS支架 颅内动脉瘤 支架辅助栓塞 

分 类 号：R651.12[医药卫生—外科学]