女性冠心病冠脉病变程度的相关血清学危险因素分析  

ANALYSIS OF RELATIONSHIP BETWEEN LEVELS OF C-REACTIVE PROTEIN,SERUM URIC ACID,FIBRINOGEN AND THE SEVERITY OF ARTERY DISEASE IN PREMENOPAUSAL AND POSTEMENOPAUSAL WOMEN WITH CORONARY DISEASE

作　　者：侯建丽 徐晓艳[2] 王静媛[2] 翁立新[2] 马秀梅[2] 李时荣[2] 

机构地区：[1]内蒙古中医院病理科,内蒙古呼和浩特010020 [2]内蒙古医科大学教研室

出　　处：《内蒙古医科大学学报》2016年第5期412-416,共5页Journal of Inner Mongolia Medical University

基　　金：内蒙古自然科学基金(2015MS0373)

摘　　要：目的:比较分析女性冠心病病人的冠脉病变特点及其与C-反应蛋白(CRP)、尿酸(UA)、纤维蛋白原(FIB)的相关性。方法:选取经冠脉造影确诊为冠心病(CHD)的女性80例,其中绝经前40例,绝经后40例,根据冠脉造影病变受累情况分为单支病变组、双支病变组、多支病变组,通过对血清中CRP、UA、FIB水平的检测,探索其与冠脉病变程度的是否存在相关性。结果:女性CHD病人血清中CRP、UA、FIB水平随冠脉病变程度的加重呈逐渐升高趋势。结论:女性CHD血CRP、尿酸、纤维蛋白原水平的升高与冠状动脉严重程度具有相关性。Objective ： To explore the relationship between levels of C-reactive protein, Serum Uric Acid, Fibrinogen and the extent and Severity of artery disease inpremenopausal and postmenopausal women with coronary disease. Methods： 80women diagnosed as coronary disease by coronary angiography were enrolled. According to coronary angiography, which was divided into two groups：pre- menopausal group （40cases） and, postmenopausal group （40cases） , which was further divided into three subgroups：single vessel disease group, double vessels disease group and multi-vessels disease group. The level of CRP, SUA and FIB were measured, and to analyze the relation Between Levels of C- reactive protein, Serum Uric Acid, Fibrinogen and the Severity of coronary artery. Results ： The levels of CRP, SUA and Fg positively related with the Severity of coronary artery. Conclusion：The level of CRP UA and FIB maybe were independent risk factors for the Severity of coronary artery.

关 键 词：女性 绝经 冠脉病变 血清学 

分 类 号：R711.52[医药卫生—妇产科学]