532 nm KTP激光治疗鲜红斑痣的自身对照研究  

Efficacy and safety of 532 nm KTP laser in the treatment of port-wine stains

作　　者：杨千里[1] 郑文渊 卢忠[1] YANG Qianli ZHENG Wenyuan LU Zhong(Department of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China The Fourth People＇s Hospital of Wenling , Zhejiang 317511, China)

机构地区：[1]复旦大学附属华山医院皮肤科,上海200040 [2]温岭市第四人民医院,浙江温岭317511

出　　处：《中国麻风皮肤病杂志》2017年第1期12-17,共6页China Journal of Leprosy and Skin Diseases

摘　　要：目的:比较532 nm KTP激光与脉冲染料激光(PDL)对鲜红斑痣的疗效及安全性。方法:将18例鲜红斑痣患者的自身皮损随机分成KTP激光治疗区及PDL治疗区,分别予以532 nm KTP激光及595 nm PDL治疗,每2~3个月治疗一次,共2~4次。每次治疗前、后即刻及治疗后2~3个月对患者激光治疗后的皮损进行疗效及安全性评价。结果:532 nm KTP激光治疗组及595 nm PDL治疗组治疗后疗效均无显著差异。在一些既往曾接受PDL治疗疗效不佳的患者,经532 nm KTP激光治疗后,皮损取得一定改善。532 nm KTP激光治疗组在治疗时疼痛程度及治疗后紫癜程度均显著低于595nmP DL治疗组。两组均有1例色素沉着发生。结论:532 nm KTP激光治疗鲜红斑痣的疗效较好,不良反应少,安全性好,可以作为鲜红斑痣治疗的另一方案。Objective： To compare the efficacy and adverse reactions of 532 nm KTP laser and 595 nm pulsed dye laser in the treatment of port wine stain. Methods： The lesions of 18 patients were divided into two areas. One area was treated with 532 nm KTP laser and another area was treated with 595 nm pulsed dye laser, onee every 2 - 3 months for 2 - 4 times. The safety and efficacy were evaluated after the treatment and in 2 -3 months after the treatment. Results： There was no significant difference in the cure rate between 532 nm KTP laser and 595 nm pulsed dye laser. Some patients who were resistant to pulsed dye laser treatment were also sensitive to the treatment with 532 nm KTP laser. There were less pain and less purpura in the group of 532 nm KTP laser. Only one patient in each group developed hyperpigmentation. Conclusion： 532 nm KTP laser has similar efficacy to 595 nm pulsed dye laser and relatively less adverse reactions. It can be used as an alternative treatment of port wine stain.

关 键 词：鲜红斑痣 532 NM KTP激光 脉冲染料激光 疗效 不良反应 

分 类 号：R758.51[医药卫生—皮肤病学与性病学]