利尿剂药物治疗高血压所致51例不良反应分析  

Analysis of 51 cases of adverse reactions of diuretics in the treatment of hypertension

作　　者：葛跃[1] 梁化强[1] 刘玮[1] GE Yue LIANG Huaqiang LIU Wei(Wanbang Biopharmaceuticals Co., Ltd., Xuzhou 221004, China)

机构地区：[1]江苏万邦生化医药股份有限公司,徐州221004

出　　处：《上海医药》2017年第3期38-40,共3页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的 :为降低利尿剂药物不良反应的发生,为其临床安全用药提供参考依据。方法 :汇总徐州市2014年7月至2016年7月共51例利尿剂药物的不良反应报告进行回顾性分析和总结。结果 :小剂量使用利尿剂药物较为安全,当剂量过大时易引起不良反应,主要表现为头痛、头晕、腹泻、电解质紊乱和高尿酸血症等。结论 :利尿剂药物应从小剂量开始服用,选择合适的利尿剂药物,加强监测,避免不良反应的发生。Objective： To reduce the occurrence of adverse reactions of diuretics and provide a basis for clinical rational drug use. Methods： The data from 51 patients with the adverse drug reactions from July, 2014 to July, 2016 in Xuzhou city were retrospectively analyzed and summarized. Results： Low-dose diuretics are safer while higher-dose tends to cause adverse reactions, which are mainly manifested as headache, dizziness, diarrhea, electrolyte disorder and hyperuricemia and so on. Conclusion： Diuretics should be taken from low dose and appropriate ones should be carefully chosen and monitoring should be also strengthened so as to avoid the occurrence of adverse reactions.

关 键 词：利尿剂药物 高血压 不良反应 

分 类 号：R544.1[医药卫生—心血管疾病]