中药熏蒸联合盐酸左氧氟沙星治疗ⅢA型前列腺炎(湿热瘀滞证)的临床疗效研究  

Traditional Chinese medicine fumigation combined with Levofloxacin for type ⅢA prostatitis with the symptoms of damp heat and blood stasis

作　　者：杨兴智[1] 郭宇[1] 熊伟[1] 李洁[2] 常德贵[3,4] 张培海[5] 王铀[1] 王曦[1] 代小红[1] 

机构地区：[1]重庆市中医院泌尿外科,重庆400021 [2]重庆市中医院内分泌科,重庆400021 [3]重庆市中医院 [4]成都中医药大学第二附属医院男科,四川成都610041 [5]四川省中西医结合医院男科,四川成都610041

出　　处：《中华男科学杂志》2017年第2期173-177,共5页National Journal of Andrology

摘　　要：目的:观察中药熏蒸联合盐酸左氧氟沙星治疗ⅢA型前列腺炎(湿热瘀滞证)的临床疗效。方法:将72例ⅢA型前列腺炎(湿热瘀滞证)患者随机分成两组,其中治疗组36例,对照组36例。治疗组采取中药熏蒸联合盐酸左氧氟沙星胶囊口服治疗,对照组单纯使用盐酸左氧氟沙星胶囊口服治疗。治疗4周后,对比两组疗效及治疗前后美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)、中医症状评分、最大尿流率(Qmax)、平均尿流率(Qave)的变化情况。结果:治疗组总有效率(91.7%)显著高于对照组(61.1%),差异有统计学意义(P<0.01)。总NIH-CPSI:治疗组治疗后为(14.5±8.2)分,显著低于治疗前的(26.5±9.3)分和对照组治疗后的(20.6±7.9)分,P均<0.05;对照组治疗前后差异无显著性[(27.1±9.1)分vs(20.6±7.9)分,P>0.05]。Qmax:对照组治疗前后无明显改变[(15.4±3.4)ml/s vs(16.1±2.9)ml/s,P>0.05],治疗组治疗后显著高于治疗前[(21.2±4.3)ml/s vs(15.8±3.6)ml/s,P<0.05],也显著高于对照组治疗后水平。Qave:对照组治疗前后也无明显改变[(10.9±2.4)ml/s vs(11.1±2.9)ml/s,P>0.05],治疗组治疗后显著高于治疗前[(16.3±3.5)ml/s vs(10.5±2.8)ml/s,P<0.05],也显著高于对照组治疗后水平。结论:中药熏蒸联合盐酸左氧氟沙星能明显改善ⅢA型前列腺炎(湿热瘀滞证)患者的症状,降低其NIH-CPSI,同时提高患者的Qmax及Qave,可作为ⅢA型前列腺炎(湿热瘀滞证)的一种有效治疗方法。Objective： To investigate the clinical effects of traditional Chinese medicine（ TCM） fumigation on type ⅢA prostatitis with the symptoms of damp heat and blood stasis. Methods： We randomly divided 72 cases of type ⅢA prostatitis with the symptoms of damp heat and blood stasis into an experimental and a control group of equal number,the former treated with TCM fumigation plus oral Levofloxacin while the latter with oral Levofloxacin only. After 4 weeks of treatment,we compared the National Institute of Health Chronic Prostatitis Symptom Index（ NIH-CPSI） score,TCM symptoms score,maxinum flow rate（ Qmax）,and average urinary flow rate（ Qave） between the two groups of patients. Results： The total effectiveness rate was significantly higher in the experimental than in the control group（ 91. 7% vs 61. 1%,P〈0. 01）,while the NIH-CPSI score in the experimental group was markedly decreased after treatment as compared with the baseline（ 14. 5 ± 8. 2 vs 26. 5 ± 9. 3,P〈0. 05） and significantly lower than that in the control（ 14. 5 ± 8. 2 vs 20. 6 ± 7. 9,P〈0. 05）. Qmax was remarkably increased in the experimental group after treatment in comparison with the baseline（ [21. 2 ± 4. 3]vs [15. 8 ± 3. 6]ml / s,P〈0. 05） and the control group,and so was Qave as compared with pretreatment（ [16. 3 ± 3. 5]vs [10. 5 ± 2. 8]ml / s,P〈0. 05） and the control. However,the patients of the control group showed no statistically significant differences before and after treatment either in Qmax（ [15. 4 ± 3. 4]vs [16. 1 ± 2. 9]ml / s,P〈0. 05） or in Qave（ [10. 9 ± 2. 4]vs [11. 1 ± 2. 9]ml / s,P〈0. 05）. Conclusion： TCM fumigation combined with Levofloxacin is an effective therapy for type ⅢA prostatitis with the symptoms of damp heat and blood stasis,which can significantly improve the symptoms,reduce the NIH-CPSI score,and increase the Qmax and Qave of the patient.

关 键 词：中药熏蒸 盐酸左氧氟沙星 ⅢA型前列腺炎 湿热瘀滞证 美国国立卫生研究院慢性前列腺炎症状指数 

分 类 号：R697.33[医药卫生—泌尿科学]