高危非致残性脑血管病及其防控关键技术与应用——2016年度国家科学技术进步二等奖  

Strategies for management of high risk nondisabling cerebrovascular events

作　　者：王伊龙[1] 赵性泉[1] 王拥军[1] 

机构地区：[1]首都医科大学附属北京天坛医院神经内科,北京100050

出　　处：《首都医科大学学报》2017年第1期1-5,共5页Journal of Capital Medical University

基　　金：国家科技支撑计划(2006BAI01A11);北京市科技计划(D101107049310005,D101107049310006,D09050703560904,D0905004040231,10910120119)

摘　　要：脑血管病已成为我国居民死亡和成人致残的首位病因,其高复发、高致残的主要原因是适宜干预人群不清、高危预警策略不明、循证治疗手段贫乏、个体化诊疗技术欠缺等。王拥军教授团队在开展大样本量社区人群调查和住院队列研究的基础上,发现了我国脑血管病防治的适宜且需重点干预人群,并以此为突破口提出了＂高危非致残性脑血管病＂概念,建立了高危风险预警体系,开创了优化的＂双重抗血小板＂治疗新技术,使高危患者90 d复发风险在不增加出血的前提下降低32%。成果改写了国际、国内指南,在临床得到广泛推广应用,已累计减少74万例脑血管病复发病例,累计降低医疗花费150亿人民币。Cerebrovascular events have become the most common cause for death or dependency of Chinese population. Risk assessment model for stroke recurrence was insufficient and effective treatment strategy was lacking. Prof. Yongjun Wang et al carried out a population-based survey and a cohort study with large sample, presented the concept of ＂high risk patients with acute nondisabling eerebrovascular events＂, established a risk accessment system for stroke, and found a new dual antiplatelet method which significantly decreased the risk of stroke recurrence by 32% without increasing bleeding events. The new method had been applied in the clinical practice widely, decreased stroke recurrence in 740 000 cases and reduced medical cost by 15 billion yuan.

关 键 词：脑血管病 高危非致残 预警 诊断 治疗 

分 类 号：R743.3[医药卫生—神经病学与精神病学]