视网膜分支静脉阻塞与颈内动脉弹性功能参数相关性研究  

Relationship between branch retinal vein occlusion and internal carotid artery elasticity

作　　者：李爽[1] 王薇[1] 洪慧[1] 赵露[1] 王艳玲[1] 

机构地区：[1]首都医科大学附属北京友谊医院眼科,北京100050

出　　处：《首都医科大学学报》2017年第1期6-10,共5页Journal of Capital Medical University

基　　金：国家自然科学基金(81173412);北京市自然科学基金(7122046)~~

摘　　要：目的探讨视网膜分支静脉阻塞与颈内动脉狭窄及颈内动脉弹性功能参数的相关性。方法选择2014年1月至2014年11月在首都医科大学附属北京友谊医院眼科确诊为视网膜分支静脉阻塞病人56例(56眼)作为研究组,对照组选取无视网膜分支静脉阻塞者36例(36眼),均进行多普勒彩超检查,测定颈内动脉的收缩期内径(systolic diameter,Ds)、舒张期内径(diastolic diameter,Dd)、收缩期血流峰值(peak systolic velocity,Vs)、舒张期血流峰值(end diastolic velocity,Vd)、平均血流速度(mean velocity,Vm)、内-中膜厚度(intima-media thickness,IMT)、斑块形成情况,计算颈内动脉弹性功能参数:管壁运动度(wall motion degree,ΔD)、动脉紧张度、扩张性、压力-应变性系数(pressure-strain elastic modulus,Eρ)、僵硬度指数(stiffness index,β)、顺应性(arterial compliance,AC)、阻力指数(resistance index,RI),将2组各指标进行比较分析。结果颈动脉斑块、颈内动脉狭窄发生比例及颈内动脉的IMT等指标,研究组明显高于对照组(P<0.05)。颈内动脉管壁运动度(ΔD)、动脉紧张度、动脉扩张性、压力-应变性系数(Eρ)及顺应性(AC)等指标,研究组与对照组比较,差异具有统计学意义(P<0.05)。研究组的平均血流速度(Vm)、阻力指数(RI)及僵硬度指数(β)与对照组比较,差异无统计学意义(P>0.05)。结论视网膜分支静脉阻塞的发生与颈内动脉狭窄及颈内动脉弹性功能参数的改变有一定的相关性。Objective To investigate the relationship between BRVO （branch retinal vein occlusion） and internal carotid artery elasticity. Methods For patients with BRVO who presented to Beijing Friendship Hospital between January 2014 and November 2014, 92 eyes of 92 patients were assigned as the participants ,56 patients with BRVO were assigned as the BRVO group,36 patients were enrolled as control. All the participants were examined with color Doppler ultrasonography , these indexes were systolic diameter（ Ds）, diastolic diameter （Dd）, peak systolic velocity（Vs）, end diastolic velocity（Vd） ,mean velocity（Vm） ,intima-media thickness（IMT） and plaque formation. These values were calculated： the internal carotid artery elastic parameters by relevant formula; wall motion degree（AD）, arterial tension, arterial expansion, pressure-strain elastic modulus （ Ep ） , stiffness index （ [3 ） , arterial compliance （ AC ） and resistance index （ RI ） , internal carotid artery elasticity parameters and other index. Results Carotid plaque detection rate ,internal carotid artery stenosis rate and intima- media thickness（IMT） of BRVO group were significantly higher than those of control group （P 〈 0. 05 ）, wall motion degree （AD）, arterial tension,arterial expansion, pressure-strain elastic modulus （EO）, and arterial compliance （AC）of BRVO group had significant differences compared with control group （ P 〈 0. 05 ） , resistance index （ RI ）, mean velocity （Vm） and stiffness index （ [3 ） of BRVO group have no significant differences compared with control group （ P 〉 0. 05 ）. Conclusion The detection of carotid artery hemodynamic parameters for patients with branch retinal vein occlusion is important, there is a relationship between BRVO and internal carotid artery elasticity.

关 键 词：视网膜分支静脉阻塞 颈内动脉 动脉弹性指标 

分 类 号：R543.4[医药卫生—心血管疾病] R774[医药卫生—内科学]