疟疾患者体内疟原虫滴度与体温及预后之间的相关性研究  

Study on correlation between plasmodium titre with body temperature and prognosis in malaria patients

作　　者：罗慧琴[1] 李玲[2] 刘付芹[2] 赵亚朴[1] 

机构地区：[1]解放军第254医院检验科,天津300142 [2]解放军第264医院检验科,太原030001

出　　处：《国际检验医学杂志》2017年第4期478-479,482,共3页International Journal of Laboratory Medicine

摘　　要：目的探讨疟疾患者体内疟原虫滴度与体温及预后之间的关系,为疟疾漏诊和误诊提供理论依据。方法收集疟疾检测阳性标本93例,利用胶体金免疫层析法和厚薄血片同时对标本进行疟原虫检测,同时记录他们体温,体温每升高1℃进行1次疟疾检测,直到疟疾检测阳性为止。结果在受检的93例标本中,中国人感染率为56.98%(53/93),外国人感染率为43.01%(40/93),中国人和外国人疟疾感染组间比较差异无统计学意义(P>0.05),说明疟疾感染与人种无关;在93例标本中,初次感染疟疾的48人,包括47个中国人,1个外国人。45人为2次或多次感染疟疾,其中滴度为1∶10的人数为33人,复发率为0.09%(3/33),再燃率为0.27%(9/33),滴度为1∶20的人数为28人,复发率为0.04%(1/28),再燃率为0.21%(6/28),滴度为1∶30的人数为19人,复发率为0.16%(3/19),再燃率为0.37%(7/19),滴度为1∶40的人数为13人,复发率为0.15%(2/13),再燃率为0.38%(5/13),复发人数与再燃人数与滴度之间比较差异无统计学意义(χ2=2.5,P>0.05;χ2=1.96,P>0.05)。结论疟疾和滴度、温度呈正相关,滴度升高,发生复发和再燃的概率增大。Objective To investigate the relationship between the Plasmodium malaria titre with the body temperature and prognosis to provide a theoretical basis for malaria diagnosis and missed diagnosis.Methods Ninety-three malaria test positive specimens were collected and simultaneously performed the plasmodium test by using the colloidal gold immune chromatography assay and thick film blood slide.The body temperature of malaria patients was recorded,and the malaria test was conducted once when the body temperature was increased by 1 ℃ until positive for malaria detection.Results In 93 tested specimens,the infection rate of Chinese was 56.98%（53/93）,and which of foreigners was 43.01%（40/93）,the difference between Chinese and foreigners malaria infection groups had no statistical significance,showing that malaria infection had no relationship with race.Among 93 specimens,the initial malaria infection was in 48 cases,including 47 Chinese and 1foreigner,and 45 cases had twice or more malaria infection,in which 33 cases had the titers of 1∶10,with the recurrence rate of 0.09%（3/33）and the re-burning rate was 0.27%（9/33）.The titer of 1∶20had 28 cases,with the recurrence rate 0.04%（1/28）,and the burning rate 0.21%（6/28）.Titer of 1∶30was 19 people,with the recurrence rate 0.16%（3/19）and the burning rate 0.37%（7/19）.The titer of 1∶40was 13 people,with the recurrence rate 0.15%（2/13）,and the re-burning rate of 0.38%（5/13）,there was no statistically significant difference between the number of recurrent and re-burning patients with the titre（χ^2=2.5,P〉0.05;χ^2=1.96,P〉0.05）.Conclusion There is a positive correlation between malaria with the titer and temperature.The titer is elevated,and the probability of recurrence and re-buring is increased.

关 键 词：国际维和 体温 疟原虫 滴度 

分 类 号：R531.3[医药卫生—内科学]