2579例Ⅰ类切口手术围术期抗菌药物预防应用分析  

Analysis of perioperative prophylactic application of antibiotics in 2 579 cases of typeⅠincision operation

作　　者：秦艳娥[1] 钟慧[1] 陈彪[1] 梁颖娥[1] 张慧玲[1] 欧瑜暇 蒋桂欢 

机构地区：[1]南宁市第一人民医院,南宁530022 [2]桂林医学院,桂林541004

出　　处：《西北药学杂志》2017年第2期234-237,共4页Northwest Pharmaceutical Journal

摘　　要：目的为进一步加强围术期抗菌药物预防性应用管理提供依据。方法抽取医院2015年出院的所有Ⅰ类切口手术病历2 579例,对围术期抗菌药物预防性应用是否有指征、预防用药品种、时机和疗程进行回顾性分析评价。结果 2015年医院Ⅰ类切口手术2 579例,其中预防用药822例,占31.87%;原则上不预防使用抗菌药物的Ⅰ类切口手术(甲状腺、乳腺、腹股沟疝和白内障手术)824例,预防用药92例,占11.16%;预防用抗菌药物以头孢唑林为主,占95.01%。预防用药不合理220例,其中预防用药超疗程占43.63%,无指征预防用药占32.73%。结论医院Ⅰ类切口手术抗菌药物预防性应用基本合理,但仍然有无指征预防用药、用药品种不适宜、用药疗程过长等不合理现象,医院应继续加强围术期抗菌药物预防性应用管理。Objective To provide reference for further strengthening the management of the perioperative prophylactic use of antibiotics in our hospital.Methods Totally 2 579 cases with typeⅠincision surgery in the hospital during Jan.2015 to Dec.2015 were retrospectively analyzed in terms of the medication indication,medical varieties,administration time and medication course.Results In 2 579 cases,there were 822 cases of perioperative prophylactic application of antibiotics with application rate of 31.87%.824 cases including thyroid surgery,breast surgery,hernia surgery and cataract surgery should not apply antibiotics in principle,but 92 cases applied.The application rate was 11.16%.Cefazolin as a main prevention drug was used in 781cases（95.01%）.The irrational drug use was 220 cases,including 43.63% long course of treatment and 32.73% non-indication application.Conclusions The perioperative prophylactic use of antibiotics for typeⅠincision operation in the hospital was basically rational.However,there were still irrational applications,including non-indication usage,irrational drug selection and too long medication course.It is necessary to further strengthen the management of perioperative prophylactic use of antibiotics in the hospital.

关 键 词：Ⅰ类切口手术 围术期 抗菌药物 

分 类 号：R969.3[医药卫生—药理学]