康艾注射液联合卡培他滨及奥沙利铂治疗晚期结肠癌临床观察  

Clinical observation of Kang'ai injection combined with capecitabine and oxaliplatin scheme in the treatment of advanced colon cancer

作　　者：丁萍[1] 鲁治文 王维民[1] 周炎[1] 

机构地区：[1]江苏大学附属宜兴人民医院肿瘤科,宜兴214200

出　　处：《陕西中医》2017年第3期351-352,共2页Shaanxi Journal of Traditional Chinese Medicine

摘　　要：目的:探讨康艾注射液联合卡培他滨及奥沙利铂(XELOX)方案治疗晚期结肠癌的临床价值。方法:对62例晚期结肠癌患者按随机数字表法分为观察组32例和对照组30例。观察组给予康艾注射液联合XELOX方案,对照组给予XELOX方案化疗,21d为1个周期,完成2个周期后评价疗效、生活质量和不良反应,并随访2年,比较生存率差异。结果:观察组的总有效率和随访1、2年的生存率均略高于对照组。观察组的生活质量改善率和化疗副反应均明显优于对照组。结论:康艾注射液有助于提高晚期结肠癌患者对化疗的耐受性,提高生活质量。Objective ：To explore the clinical value of Kang＇ai injection combined with XELOX （Capecitabine ＋Oxaliplatin） scheme in the treatment of advanced colon cancer .Methods ：62 cases with advanced colon cancer were randomly divided into the observation group and the control group .The control group were treated with XELOX scheme ,while the observation group were added with Kang＇ai injection based on the same chemotherapy ,21 days for 1 cycles .The efficacy ,quality of life and adverse reactions were evaluated after 2 cycles .After two years of follow-up ,the survival rate of the two groups was compared .Results ：The effective rates and the survival rates of 1 ,2 years in the observation group were slightly higher than that of the control group ,there was no statistical difference in the above results .The improvement rate of life quality and side effects of chemotherapy in the observation group were significantly better than those in the control group ,the differences were statistically significant .Conclusion ：Kang＇ai injection can improve the tolerance of advanced colon cancer to chemotherapy ,reduce adverse reactions and improve the quality of life .

关 键 词：结肠肿瘤/中西医结合疗法 @康艾注射液 卡培他滨 奥沙利铂 

分 类 号：R273[医药卫生—中西医结合]