地黄不同炮制品配方颗粒的红外快速鉴别  

Rapid Identification of Different Processed Products of Rehmannia Glutinosa Formula Granules by FTIR

作　　者：周明霞 高会芹 彭雄颖 李亚涛 李军山 屈云萍 李振江 

机构地区：[1]神威药业集团有限公司,河北石家庄051430 [2]河北省中药配方颗粒工程技术研究中心,河北石家庄050200

出　　处：《中国药物警戒》2017年第2期87-89,94,共4页Chinese Journal of Pharmacovigilance

基　　金：河北省中医药管理局科研计划项目(中药配方颗粒与传统汤剂(中成药)等效性对比研究:2016297)

摘　　要：目的建立红外光谱法快速鉴别地黄不同炮制品配方颗粒的方法。方法采用红外光谱结合二阶导数光谱及二维相关光谱法分析不同炮制品配方颗粒光谱特征。结果二阶导数光谱在1 200~1 800 cm^(-1)范围内差异较大,二维相关光谱图差异明显。结论通过比较不同炮制品红外光谱图、二阶导数光谱图及二维相关光谱图,可以准确、快速鉴别地黄不同炮制品配方颗粒。Objective To establish a rapid FTIR method for identifying different processed products of R chm annia g lu tin o sa formula granules. Methods Various processed products were researched by infrared, second derivative spectra and twodimensional correlation spectroscopy. Results In second derivative spectra, it existed differences among the intensity, shape and position of the peaks in the range of 1 200 ？1 800 cm＇ and the two-dimensional correlation spectroscopy were different obviously. Conclusion By comparing the infrared spectra, second derivative spectra and two-dimensional correlation spectroscopy, the different processed products of Rehmannia gltinosa formula granules could be identified rapidly and accurately.

关 键 词：傅里叶变换红外光谱法 二阶导数光谱 二维光谱 地黄 配方颗粒 

分 类 号：R927[医药卫生—药学]