不同的治疗方案抢救重度急性有机磷杀虫药中毒的疗效比较  

Effect Comparison of Different Therapeutic Schemes in the Treatment of Severe Acute Organophosphorus Pesticide Poisoning

作　　者：吴明先[1] 冉小于 郑涛[1] 

机构地区：[1]达州市中心医院急诊科,四川达州635000

出　　处：《继续医学教育》2017年第2期152-154,共3页Continuing Medical Education

摘　　要：目的探讨不同治疗方案抢救重度急性有机磷杀虫药中毒的疗效。方法选取我院急诊科于2014年9月—2016年9月收治的60例重度急性有机磷杀虫药中毒的患者为研究对象,随机分为观察组和对照组,各30例。对照组给予氯解磷定(常规剂量),观察组氯解磷定(突击剂量)。比较两组的治疗效果。结果观察组的阿托品用量少于对照组,阿托品化时间、住院时间短于对照组,差异有统计学意义(P<0.05)。观察组治疗24 h、48 h后的Ch E高于对照组,差异有统计学意义(P<0.05)。两组的IMS、死亡率、不良反应比较差异无统计学意义(P>0.05)。结论合理应用氯解磷定能够减少有机磷杀虫药中毒患者的阿托品用量,促进Ch E恢复,缩短住院时间。Objective To investigate the effect comparison of different therapeutic schemes in the treatment of severe acute organophosphorus pesticide poisoning. Methods 60 cases of severe acute organophosphorus pesticide poisoning patients in our hospital from September 2014 to September 2016 were randomly divided into the observation group and the control group, 30 cases in each group. The control group was given chloride solution phosphorus （conventional dose）, the observation group of chloride solution phosphorus （assault dose）. The two groups were compared of the treatment effect. Results The dosage of atropine in the observation group was less than that in the control group, the time of atropine and the hospitalization time was shorter thanthat in the control group, the difference had statistically significant （P〈0.05）. ChE after 24 h and 48 h of the treatment in the observation group was higher than that in the control group, the difference had statistically significant （P〈0.05）. There was no significant statistical significance （P〉0.05） in the two groups of IMS, mortality and adverse reactions. COnclusion Rational application of chloride solution can reduce the dosage of atropine in patients with organophosphorus pesticide poisoning, which can promote the recovery of ChE and shorten the length of hospital stay.

关 键 词：不同治疗方案 重度 急性有机磷杀虫药中毒 疗效 

分 类 号：R971[医药卫生—药品]