AFB_1降解剂对肉鸡生长性能、养分代谢及AFB_1在体内残留的影响  

Effect of AFB_1-degrading Agent on Growth Performance,Nutrients Metabolism and AFB_1 Residues in Broiler

作　　者：左瑞雨[1,2] 王秋文[1] 常娟[1] 尹清强[1] 王二柱 朱群 

机构地区：[1]河南农业大学牧医工程学院,郑州450002 [2]河南省畜牧总站,郑州450008 [3]河南德邻生物制品有限公司,新乡453000

出　　处：《中国畜牧兽医》2017年第2期432-439,共8页China Animal Husbandry & Veterinary Medicine

基　　金：基金项目:郑州市科技创新团队(112PCXTD339)

摘　　要：通过在含有黄曲霉毒素B_1(aflatoxin B_1,AFB_1)的肉鸡日粮中添加AFB_1降解剂,测定其对肉鸡生长性能、养分代谢及AFB_1在血液、肝脏及肌肉中残留的影响。试验选择42日龄健康AA肉鸡75只随机分为5组,每组设5个重复。A组为对照组,饲喂基础日粮,B、C、D和E组在基础日粮中分别添加400、200、400和800μg/kg AFB_1。B组为负对照组,C、D和E组分别添加0.15%AFB_1降解剂,试验期为30d。试验结束时,测定肉鸡的生长性能、营养物质代谢率、体内AFB_1含量及抗氧化酶活性。结果表明:与AFB_1含量相同的B组相比,D组的平均日采食量和末重分别提高了32.45%、42.46%(P<0.05);与B组相比,其余各组的有机物、粗蛋白质、钙和磷的代谢率均有显著提高(P<0.05),D组的有机物和粗蛋白质消化率分别提高了9.50%和178.75%(P<0.05)。血液、组织中AFB_1的测定结果表明,停喂AFB_1前,C组肝脏中AFB_1含量显著低于B组(P<0.05),停喂AFB_124h后,A和C组胸肌中AFB_1含量显著低于B、D和E组(P<0.05),停喂AFB_148h后,C、D组胸肌中AFB_1含量恢复到与对照组相同的水平。与B组相比,添加0.15%AFB_1降解剂的C、D和E组,血清和肝脏中谷胱甘肽过氧化物酶和超氧化物歧化酶活力显著提高(P<0.05)。由此可见,在含有AFB_1的日粮中添加AFB_1降解剂,可缓解AFB_1对生长的抑制,提高养分消化率,加速AFB_1在肉鸡体内的代谢,减少AFB_1对机体的损伤。Effects of aflatoxin B1（AFB1）-degrading agent on growth performance,nutrients metabolism and AFB1 residues in blood,liver and muscles were studied by adding it in broiler diets infected AFB1.Seventy five 42-day-old Arbor Acres（AA）broilers were randomly allocated to 5groups with 5replicates per group.Broilers in group A（control group）were fed with basic diet,the diets of group B（negative control group）,C,D and E were supplemented with 400,200,400 and 800μg/kg AFB1,and broilers in group C,D and E were fed with the diets containing 0.15%AFB1-degrading agent,respectively.The experiment lasted for 30 d.Growth performance,nutrient metabolic rate,AFB1 contents and antioxidant indices were measured at the and of experiment.The results indicated that,compared with group B,the final weight and average daily feedintake of group D were increased by 32.45% and 42.46%（P〈0.05）,and the metabolic rates of organic matter,crude protein,calcium and phosphorus in other groups were significantly increased（P〈0.05）,the metabolic rates of organic matter and crude protein in group D increased by 9.50% and 178.75%（P〈0.05）.Liver AFB1 content in group C was significant lower than that in group B（P〈0.05）.The breast muscle AFB1 contents in group A and C were significant lower than that in other groups（P〈0.05）at 24 hafter AFB1administration termination.The breast muscle AFB1 contents in group C and D were similar to the control group at 48 hafter AFB1administration termination.Compared with group B,SOD,GSH-Px activities of serum and liver in group C,D and E were significantly increased（P〈0.05）.It was concluded that adding AFB1-degrading agent in diets could increase broiler growth and nutrient availability,accelerate AFB1 metabolism,and reduce the harmful effect of AFB1 on broilers.

关 键 词：AFB1降解剂 肉鸡 生长性能 代谢率 

分 类 号：S816.7[农业科学—饲料科学]