加大翻转角对缩短Gd-EOB-DTPA肝胆期延迟时间的可行性研究  

The feasibility study of shortening delay time of hepatobiliary phase by increasing flip angle on Gd-EOB-DTPA-enhanced MRI

作　　者：崔恩铭[1] 龙晚生[1] 李卓永[1] 罗学毛[1] 兰勇[1] 黄列彬 胡茂清[1] 

机构地区：[1]江门市中心医院放射科,广东529030

出　　处：《放射学实践》2017年第2期153-156,共4页Radiologic Practice

摘　　要：目的:探讨加大翻转角(FA)扫描对缩短钆塞酸二钠(Gd-EOB-DTPA)肝胆期延迟时间的可行性。方法:对71例患者(共107个病灶)分别行延迟10min FA20°和FA30°、延迟20min FA10°Gd-EOB-DTPA肝胆期成像,计算并比较3组扫描方式的肝信噪比(SNR_肝)、病灶信噪比(SNR_(病灶))、肝-病灶比值(LLR)、胆道-同层脊柱旁肌肉比值(BMR)。由2名放射诊断医师对所有图像进行独立判定,对比分析3组扫描的肝内病灶检出率。结果:10min FA30°组的LLR高于10min FA20°组和20min FA10°组(P均<0.05),但其SNR_肝、SNR_(病灶)明显低于10min FA20°组和20min FA10°组(P均<0.001);20min FA10°组的BMR明显高于10min FA30°组和10min FA20°组(P均<0.001);10min FA20°组和20min FA10°组组间LLR、SNR_肝、SNR_(病灶)均无统计学差异(P均>0.05)。3组扫描方式的总病灶检出率、不同大小的病灶检出率均无统计学差异(P均>0.05)。结论:10min FA20°扫描组的SNR及病灶检出率与20min FA10°扫描组相似,10min FA20°能替代20min FA10°从而缩短Gd-EOB-DTPA肝胆期延迟时间,但10min FA20°扫描显示胆道能力有限。Objective：The explore the feasibility of shortening the delay time of hepatobiliary phase by increasing flip angle（FA）on Gd-EOB-DTPA-enhanced MR imaging.Methods：Seventy-one patients with 107 hepatic lesions underwent gadoxetic acid-enhanced MRI with 10 min FA 20°,10 min 30°and 20 min FA 10°.Signal-to-noise ratio of liver（SNRliver）,signal-to-noise ratio of lesion（SNRlesion）,liver-to-lesion ratio（LLR）,bile-to-paravertebral muscle ratio（BMR）were calculated and statistically analyzed in three image groups.Two radiologists independently assessed and compared the detection rate of hepatic lesions between the three groups.Results：LLR in 10 min FA 30°group was significantly higher than those in groups10 min FA 20°and 20 min FA 10°（P〈0.05）.SNRliverand SNRlesionin 10 min FA 30°groups were much lower than those in10 min FA 20°and 20 min FA 10°groups significantly（both P〈0.001）.BMR in 20 min FA 10°group was significantly higher than those in 10 min FA 20°and 10 min FA 30°groups（P〈0.001）.There was no significant difference of LLR,SNRliverand SNRlesionbetween 10 min FA 20°and 20 min FA 10°groups（P〉0.05）.Among the three groups,there was no significant difference in the general detection rate of hepatic lesion and the detection rate of different hepatic lesion size（P〉0.05）.Conclusion：The SNR and detection rate in 10 min FA 20°group are similar to those in 20 min FA 10°group.10 min FA 20°can replace 20 min FA 10°and shorten the delay time of hepatobiliary phase,but it has poor ability to assess the bile duct.

关 键 词：翻转角 钆塞酸二钠 磁共振成像 可行性研究 

分 类 号：R445.2[医药卫生—影像医学与核医学]