脓毒症和脓毒症相关性脑病  

Sepsis and sepsis associated encephalopathy

作　　者：周业庭[1] 王光胜[2] 王少丹[3] 童道明[2] 

机构地区：[1]江苏省沭阳县人民医院普外科,223600 [2]江苏省沭阳县人民医院神经内科,223600 [3]江苏省沭阳县人民医院重症监护科,223600

出　　处：《中华脑科疾病与康复杂志（电子版）》2016年第3期173-176,共4页Chinese Journal of Brain Diseases and Rehabilitation（Electronic Edition）

基　　金：江苏省临床重点专科建设项目(20160017)

摘　　要：脓毒症定义为宿主对感染的反应失调引起的威胁生命的器官功能障碍,分为全身炎症反应综合征（SIRS）阳性和阴性两个类型。脓毒症仍是全球广泛流行的危重症之一,大约70%的脓毒症可能诱发一种脓毒症相关性脑病,病死率高达51.0%～71.9%。脓毒症和脓毒症相关性脑病常复杂多变,诊断困难。临床上,采用SIRS-阳性和SIRS-阴性脓毒症分类诊断标准,可减少脓毒症和脓毒症相关性脑病的漏诊。Sepsis is defined as a life-threatening organ dysfunction due to a dysregulated host response to infection. Sepsis is classified as systemic inflammatory response syndrome（ SIRS）-positive sepsis and SIRS-negative sepsis. Sepsis is still a critical ill in the world,about 70% of sepsis may induce sepsis associated encephalopathy,with mortality rate as high as 51. 0%-71. 9%. Sepsis and sepsis associated encephalopathy are often complex and changeable,and the diagnosis is elusive. Clinically,the classification criteria for SIRS-positive and SIRS-negative sepsis can reduce the missed diagnosis of sepsis and sepsis associated encephalopathy.

关 键 词：脓毒症 全身炎症反应综合征 诊断 预后 脓毒症相关性脑病 

分 类 号：R459.7[医药卫生—急诊医学] R747.9[医药卫生—治疗学]