口服苏打水和补液盐预防运动性横纹肌溶解症的作用观察  

Effect observation of oral rehydration salt water and carbonated water to prevent exercise-induced rhabdomyolysis

作　　者：刘长青 马丽 尹怡红 

机构地区：[1]武警8680部队医院急诊科,河南巩义451200

出　　处：《临床急诊杂志》2017年第1期9-13,17,共6页Journal of Clinical Emergency

基　　金：国家自然科学基金(No:81071585);解放军总医院科技创新苗圃基金(No:08MP26)

摘　　要：目的:探讨口服苏打水和补液盐预防运动性横纹肌溶解症的作用。方法:2016年7月将400名战士随机分为4组,每组各100名,同时进行5km越野长跑,在运动过程中4组给予不同口服液:A组饮用白开水,B组饮用口服补液盐,C组饮用口服苏打水,D组饮用补液盐加苏打水。运动结束后记录运动时间,立即进行生命体征检测,包括血压、呼吸、脉搏、体温。于运动前及结束后12h、24h、48h、72h分别检测4组战士的肌酸激酶(CK)的动态变化。统计每个战士肌肉酸痛持续时间。结果:4组战士运动时间、运动结束时体温、脉搏、呼吸、血压等比较,差异均无统计学意义。运动后12h、24h、48h、72h,4组患者CK水平比较,差异均有统计学意义(均P=0.000),CK的波峰A>B>C>D。D组肌肉酸痛持续时间短于A组(P=0.036)。结论:在运动过程中口服苏打水和补液盐可以降低运动后CK的波峰,减轻横纹肌的损伤,缩短了肌肉酸痛时间,对预防横纹肌溶解症有一定效果,合用较单用一种效果好。Objective：To study the effect of oral rehydration salt water and carbonated water to prevent exercise-induced rhabdomyolysis.Method：July 2016,400 soldiers were randomly divided into four groups,100 cases in each group,and had a 5km cross-country race,4groups were given different oral liquid,A group drank boiled water,B group drank oral liquid salt,C group drank carbonated water,D group drank oral rehydration salt water and carbonated water.Recorded the time of movement after the end of the exercise,immediately carried out vital signs detection：including blood pressure,respiration,pulse,body temperature.The changes of creatine kinase（CK）in the4 groups were detected before and after exercise at 12 h,24h,48 h,72h.The duration of muscle pain in each soldier were counted.Result：The difference was not statistically significant comparison of exercise time,temperature,pulse,breathing,blood pressure in the four groups at the end of the exercise.The differences were statistically significant compared with the CK level in the four groups after exercise 12 h,24h,48 h,72h（all P=0.000）,CK wave crest A〉B〉C〉D.The duration of muscle pain in D group was shorter than that in A group（P=0.036）.Conclusion：Oral rehydration salt water and carbonated water can reduce the peak of CK after exercise,reduce the damage of striated muscle,shorten the time of muscle ache,have a certain effect on the prevention of rhabdomyolysis,the combination is better than the one with one effect.

关 键 词：运动 横纹肌溶解症 口服补液盐 碳酸氢钠液 肌酸激酶 

分 类 号：R685.5[医药卫生—骨科学]