口服复方丹参滴丸联合羟苯磺酸钙治疗糖尿病患者视网膜病变的临床研究  

Clinical study on the treatment of diabetic retinopathy by oral compound Danshen Dripping Pill combined with calcium dobesilate

作　　者：阮余霞[1] 陈明[1] 刘志谦[1] 王永力[1] 孙念[1] 黄鑫[1] 甘浩[1] 

机构地区：[1]江汉大学附属第三医院眼科,湖北武汉430300

出　　处：《中南医学科学杂志》2017年第1期18-20,23,共4页Medical Science Journal of Central South China

摘　　要：目的观察复方丹参滴丸以及羟苯磺酸钙对糖尿病视网膜病变患者的临床应用疗效。方法收集本院糖尿病有视网膜病变患者70例,随机的均分为用羟苯磺酸钙治疗组(对照组),用羟苯磺酸钙联合复方丹参滴丸治疗组(观察组)。两组患者分别治疗4个月后,观察并分析患者的视野变化、眼底病变、不良反应、复发的情况,并检测患者的糖化血红蛋白、血糖、血脂与血压的控制水平。结果与治疗前比较,两组患者在治疗后病情均有所改善;与对照组比较,观察组眼底出血斑、视野灰度、血管瘤等治疗效果显著(P<0.05);糖化血红蛋白、血糖、血压与总胆固醇的控制均有所改善,未见不良反应发生,且复发率也低。结论用复方丹参滴丸联合羟苯磺酸钙治疗糖尿病视网膜病变疗效优于单用羟苯磺酸钙。Objective To observe the therapeutic effect of Compound Danshen Dripping Pill and calcium dobesilate on the diabetic retinopathy patients. Methods 70 cases of patients suffering from diabetic retinopathy in our hospital were randomly divided into calcium dobesilate treatment group（ control group） and combination calcium dobesilate and compound Danshen Dripping Pill treatment group（ observation group）.After treatment for 4 months,changes of visual field and fundus disease,adverse reaction and recurrence in patients were analyzed.Meanwhile,the glycosylated hemoglobin,blood glucose,and blood lipid and blood pressure were tested. Results Compared to the pretreatment,the patients condition of the two groups were improved.Compared to the control group,the therapeutic effects of bleeding spots,vision gray,hemangioma in the observation group was significantly improved（ P0.05）,control of glycosylated hemoglobin,blood glucose,blood lipid and blood pressure were restored,and the adverse reaction was not observed,and the recurrence rate was also low. Conclusion The therapeutic effect of Combination of Compound Danshen Dripping Pill and calcium dobesilate on the diabetic retinopathy patients was better than calcium dobesilate alone in treatment of patients suffering from diabetic retinopathy.

关 键 词：复方丹参滴丸 羟苯磺酸钙 视网膜病变 疗效 

分 类 号：R587.2[医药卫生—内分泌]