血培养报阳时间及病原菌分布  

Positive alarming time of blood culture and distribution of pathogens

作　　者：徐权 谭思源 陈宗宁 吴健 夏晓燕 

机构地区：[1]盐城市第一人民医院,江苏盐城224001

出　　处：《中国感染控制杂志》2017年第2期173-175,178,共4页Chinese Journal of Infection Control

基　　金：2015年盐城市科技立项(YK2015003);江苏省重点专科开放课题

摘　　要：目的了解血培养阳性标本的菌群分布及报阳时间,为实验室病原菌诊断及临床制定治疗方案提供依据。方法收集2015年5—11月某院临床各科室送检的血标本,记录血培养报阳时间并将所获得病原菌鉴定至菌种。结果从血培养标本中共分离157株病原菌,其中革兰阳性球菌占31.85%,革兰阴性杆菌占57.32%,真菌占10.83%。培养阳性病原菌及其报阳的中位时间分别为:肠杆菌科细菌0.50 d,非发酵菌0.63 d,肠球菌属0.60 d,链球菌属0.80 d,葡萄球菌属1.01 d,真菌1.44 d。结论血培养阳性标本报阳时间从早到晚依次是:肠杆菌科细菌、肠球菌属、非发酵菌属、链球菌属、葡萄球菌属、真菌。引起血流感染的病原菌均在4 d内仪器阳性报警,大多数病原菌在1 d内报阳性。ObjectiveTo investigate the distribution of pathogens and positive alarming time of blood culture, and provide basis for laboratory diagnosis and clinical treatment. MethodsBlood specimens from clinical departments in a hospital in MayNovember 2015 were collected, positive alarming time of blood culture was recorded, species of pathogens were identified. ResultsA total of 157 pathogenic strains were isolated from blood culture specimens, grampositive cocci, gramnegative bacilli, and fungi accounted for 31.85%, 57.32%, and 10.83% respectively. The median positive alarming time were as follows： Enterobacteriaceae 0.50 day, nonfermenting bacteria 0.63 day, Enterococcus spp. 0.60 day, Streptococcus spp. 0.80 day, Staphylococcus spp. 1.01 days, and fungi 1.44 days, respectively. ConclusionPositive alarming time of blood culture specimens from early to late are as follows： Enterobacteriaceae, Enterococcus, nonfermentative bacteria, Streptococcus spp., Staphylococcus spp., and fungus. Positive alarming time of pathogens causing bloodstream infection are all within 4 days, and most of them are within 1 day.

关 键 词：血培养 病原菌 菌群分布 报阳时间 中位时间 

分 类 号：R446.5[医药卫生—诊断学]