超微血管成像技术在乳腺癌新辅助化疗疗效评估中的价值  

Value on the therapeutic effectiveness of neoadjuvant chemotherapy in patients with primary breast carcinoma by superb microvascular imaging

作　　者：袁惠[1] 马芸[1] 陈洪艳[1] 田睿[1] 

机构地区：[1]昆明医科大学第一附属医院,云南昆明650032

出　　处：《中国临床医学影像杂志》2017年第2期99-100,104,共3页Journal of China Clinic Medical Imaging

摘　　要：目的:探讨超微血管成像技术在乳腺癌新辅助化疗(Neoadjuvant chemotherapy,NAC)疗效评估中的应用价值。方法:对57例乳腺癌患者73个肿瘤行NAC前后采用超微血管成像技术(Superb microvascular imaging,SMI)检查,对肿瘤最大径线、血流分级及血流动力学参数进行分析。结果:73个肿瘤NAC后最大径线较NAC前缩小;行彩色模式SMI检查显示化疗后血流分级(以0级、Ⅰ级为主)较化疗前(以Ⅱ级、Ⅲ级为主)下降,肿瘤内血流动力学参数Vmax、RI均降低(P<0.05)。超声评价本组中完全缓解21例,部分缓解37例,总有效率79.5%,与病理评价结果一致性较好。结论:SMI为临床评估乳腺癌NAC疗效提供了一种无创、快捷、有效的检查方法。Objective： To investigate the application value of the therapeutic effectiveness of neoadjuvant chemotherapy （NAC） in patient with primary breast carcinoma by superb microvascular imaging. Methods： Seventy-three primary breast carcinoma lesions were imaged by using superb microvaseular imaging in 57 patients with post- and prior-NAC treatment. The maximum diameters, blood flow classification and hemodynomics parameter of lesion were studied. Result： The maximum diameters of 73 post-NAC treatment were less than those of prior-NAC treatment. The blood flow classification（majority, 0 or 1 level） and blood flow parameters Vmax and RI of lesions in post-NAC treatment were lowered than those in prior-NAC treatment （P〈0.05）. The effective rate were 79.5%（21 cases with complete response and 37 cases with partial response）. This result was good consistency with pathology evaluate resuhs. Conclusion： Superb microvascular imaging may evaluate therapeutic effectiveness of NAC in patients with primary breast carcinoma by using way of non-invasively, speed and effective method.

关 键 词：乳腺肿瘤 抗肿瘤联合化疗方案 超声检查 多普勒 彩色 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]