药物不良反应326例报告分析  

Analysis of 326 Cases of Adverse Drug Reactions

作　　者：吴国海[1] 郭蓉[1] 陈璐[1] 史文慧[1] 

机构地区：[1]北京军区北戴河疗养院药剂科,河北秦皇鸟066100

出　　处：《解放军药学学报》2017年第1期99-101,共3页Pharmaceutical Journal of Chinese People's Liberation Army

摘　　要：目的分析药物不良反应发生的特点和规律,促进临床安全用药。方法对2014年1月—2015年12月北京军区北戴河疗养院326例药物不良反应报告,按年龄、性别、给药途径、引发药物不良反应情况及转归、药物品种分类、心血管系统药物分布、抗感染药物分布、系统损害等进行统计分析。结果326例药物不良反应给药途径以静脉用药最高,占50.00%;新的、严重的药物不良反应82例,占25.15%。326例药物不良反应患者涉及药物15大类,其中心血管系统药物药物不良反应居首位,占30.67%;抗感染药物药物不良反应排第二,占23.62%;药物不良反应系统损害分布情况以肝胆系统损害为主,占54.94%。结论应加强药物不良反应的监测工作,促进临床合理用药。Objective To analyze the characteristics and patterns of adverse drug reactions（ADRs） that have occurred at our hospital in order to promote clinical medication safety.Methods Between January 2014 and December 2015,326 cases of ADRs were reported in our hospital. These cases were statistically analyzed according to age, gender, route of administration, causes of ADRs, drug classification, distribution of cardiovascular drug,anti-infective drug distribution and system damage.Results ADRs caused by intravenous administration were the most prevalent,accounting for 50.00%.There were 82 cases of new and serious ADRs,accounting for 25.15%.Fifteen categories of drugs were involved,including cardiovascular drugs that took the first place, accounting for 30.67%.Followed by anti-infectives that accounted for 23.62%.The hepatobiliary system was the most vulnerable to ADRs, accounting for 54.94%.Conclusion Surveillance of ADRs should be enhanced to promote rational drug use.

关 键 词：药物不良反应 药物不良反应监测 合理用药 

分 类 号：R969.3[医药卫生—药理学]