2010～2015年北京石景山地区血培养菌群分布的变迁  

Changes of the distribution of blood culture bacteria in Shijingshan district of Beijing from 2010 to 2015

作　　者：农金轻 张丹[2] 祝振忠[2] 郑燕蓉[1] 

机构地区：[1]北京大学首钢医院检验科,北京100144 [2]北京大学首钢医院急诊科,北京100144

出　　处：《中国医药科学》2017年第1期113-116,共4页China Medicine And Pharmacy

摘　　要：目的总结2010~2015年北京石景山地区血培养菌群分布的变迁,以便为临床诊治提供依据。方法采用BD BACTEC 9050型全自动血培养仪对2010~2015年北京大学首钢医院的临床标本进行培养,并按照2010年美国CLSI标准及BD Phoenix 100细菌鉴定药敏分析仪进行判定分析。结果 2010~2015年,全院血培养总数量逐年递增,送检前三名科室依次为ICU、呼吸、血液科,近年来RICU血培养数量直线上升;大肠埃希氏菌数量6年来稳居第一;血培养感染谱前三名从大肠埃希氏菌、表皮葡萄球菌、金黄色葡萄球菌向大肠埃希氏菌、肺炎克雷伯杆菌、鲍曼不动氏菌变迁。结论 2010~2015年北京石景山地区血培养菌群分布从球菌向杆菌变迁,临床应据此合理选择抗生素。Objective To summarize the changes of drug resistance of positive bacteria in blomt culture in Shijingshan area of Beijing in 2010-2015, so as to provide evidence for clinical diagnosis and treatment. Methods Clinical specimens of this hospital were cultured with BD BACTEC 9050 automatic blood culture instrument from 2010 to 2015. The results were analyzed according to the CLSI standards in 2010 and BD Phoenix 100 of United States. Results From 2010 to 2015, the number of blood culture in this hospital increased year by year. The top three departments were ICU, respiratory department and hematology department. The number of blood culture from RICU increased tremendously in recent years. The number of Escherichia coli in blood culture ranked first in recent 6 years. Blood culture infection spectrum changed from Escherichia coli, Staphylococcus epidermidis, Staphylococcus anreus to Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii. Conclusion From 2010 to 2015, the blood culture infection spectrum in Shijingshan district in Beijing has changed from coccohacteria to bacillus. Antibiotics should be chosen reasonably according to the above changes.

关 键 词：血培养 菌群分布 变迁 北京石景山 

分 类 号：R446.5[医药卫生—诊断学]