外表面钝化SBA-15固载奎宁催化不对称Michael加成反应  

Outer-passivated SBA-15 supported quinine catalyst for asymmetric Michael addition reactions

作　　者：辛翠[1] 

机构地区：[1]湖南警察学院刑事科学技术系,湖南长沙410138

出　　处：《化学研究》2017年第1期31-34,共4页Chemical Research

摘　　要：以聚环氧乙烷-聚环氧丙烷-聚环氧乙烷三嵌段共聚物(P123)为模板剂制备SBA-15分子筛,将未除模板剂的SBA-15用三甲基氯硅烷钝化后固载奎宁制得外表面钝化CH_3-SBA-15-QN非均相催化剂.对非均相催化剂进行XRD、FT-IR、N_2吸附-脱附表征.并以查尔酮类化合物与丙二腈的不对称Michael加成反应为模型来考察非均相催化剂CH_3-SBA-15-QN的催化活性,实验结果表明,非均相催化剂CH_3-SBA-15-QN比SBA-15-QN催化剂对产物表现出较高的对映选择性.4-甲氧基查耳酮为底物时,CH_3-SBA-15-QN为催化剂时,产物对映选择性能够达到77%,甚至比均相催化剂高6%,充分发挥了载体孔道效应和手性催化剂的不对称诱导能力.The modified mesoporous zeolite SBA-15 was synthesized using PEO-PPO-PEO as the template,and quinine was immobized on the outer-passivated SBA-15 by trimethyl chlorosilane to ensure that catalyst could be anchored inside the SBA-15 channels. The heterogeneous catalyst was characterized by XRD,IR and N2 sorption,and evaluated in the asymmetric Michael additions of malononitrile to chalcones. For various chalcones,although the catalytic activities were lower than the conventional catalyst,higher enantioselectivities were achieved. In particular,when the 4-methoxy chalcone was test,the best ee value up to 77% was obtained. The pore effect of the carrier and the asymmetric ability of the chiral catalyst were demonstrated.

关 键 词：SBA-15 奎宁 固载化 催化 不对称MICHAEL加成 

分 类 号：O643[理学—物理化学]