定期无偿献血对献血者血清蛋白及糖脂代谢的影响  

Impact of Regular Blood Donation on Serum Protein and Lipid Metabolism

作　　者：刘磊[1] 李拴林[1] 高宏[1] 

机构地区：[1]宝鸡市中心血站,陕西宝鸡721006

出　　处：《医学综述》2017年第4期785-787,791,共4页Medical Recapitulate

摘　　要：目的探讨定期无偿献血对献血者血清蛋白及糖脂代谢的影响。方法选取2015年6—10月在宝鸡市中心血站定期参与无偿献血的献血者120例为研究对象,同期选取120例无献血史的正常体检者为对照组,测定两组研究对象血清总蛋白、铁蛋白、白蛋白、球蛋白、空腹血糖(FBG)、糖化血红蛋白(Hb A1c)、三酰甘油、总胆固醇、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平。结果两组血清铁、血清总蛋白、白蛋白、球蛋白、三酰甘油、总胆固醇、HDL-C水平比较差异无统计学意义(P>0.05),献血组血清铁蛋白、FBG、HbA1c、LDL-C、LDL-C/HDL-C水平低于对照组[(113±22)g/L比(165±25)g/L、(4.2±1.0)mmo/L比(5.3±1.2)mmol/L、(3.3±0.7)%比(4.4±0.8)%、(2.84±0.26)mmol/L比(3.82±0.24)mmol/L、(1.45±0.31)比(1.98±0.42)](P<0.05)。结论定期无偿献血者献血后血清铁蛋白、血糖水平、LDL-C以及LDL-C/HDL-C较正常非献血人群低,但均在合理范围内。通过献血可减少血清铁存储量,改善献血者血糖及脂肪水平,因此定期献血有益于健康。Objective To investigate the impact of regular blood donation on serum protein and lipid metabolism.Methods Total of 120 cases of regular blood donation from June to October 2015 were selected from Baoji blood center,and 120 persons without blood donation history were included as a control group. The levels of total protein,ferritin,albumin,globulin,fasting blood glucose（ FBG）,glycated hemoglobin（ Hb A1c）,triacylglycerol（ TG）,total cholesterol（ TC）,low-density lipoprotein-cholesterol（ LDL-C）,high-density lipoprotein-cholesterol（ HDL-C） of the two groups were detected and the effect of regular blood donation on serum protein and lipid metabolism. Results The blood serum iron,serum total protein,albumin,globulin,triglycerides,total cholesterol,HDL-C levels of the blood donation group and control group had no statistically significant difference（ P〈0. 05）,the blood serum ferritin,FBG,Hb A1 c,LDL-C,LDL-C/HDL-C levels of the blood donation group were lower than those of the control group [（ 113 ± 22） g / L vs（ 165 ± 25） g / L,（ 4. 2 ±1. 0） mmo / L vs（ 5. 3 ± 1. 2） mmol / L,（ 3. 3 ± 0. 7） % vs（ 4. 4 ± 0. 8） %,（ 2. 84 ± 0. 26） mmol / L vs（ 3. 82 ±0. 24） mmol / L,（ 1. 45 ± 0. 37） vs（ 1. 98 ± 0. 42）,P〈0. 05]. Conclusion The levels of blood serum ferritin,Hb A1 c,LDL-C,LDL-C / HDL-C of the blood donation persons are lower than the non-blood donation persons,but all in reasonable range. Blood donation can reduce the serum iron reserve,improve the levels of blood glucose and fat levels,so regular blood donation is good for health.

关 键 词：定期无偿献血 血清蛋白 血糖 血脂 

分 类 号：R115[医药卫生—公共卫生与预防医学]