保留子宫韧带血管的子宫体大部切除术治疗子宫良性疾病的疗效  

Clinical Effect of Large Partial Excision of Uterine Body with the Reservation of the Uterine Ligament for Treatment of Benign Uterine Disease

作　　者：吴涛[1] 薛蕾蕾[1] 

机构地区：[1]鞍山市中心医院妇产科,辽宁鞍山111400

出　　处：《医学综述》2017年第4期817-820,共4页Medical Recapitulate

摘　　要：目的分析保留子宫韧带血管的子宫体大部切除术治疗子宫良性疾病的临床疗效。方法选取2013年1月至2014年10月鞍山市中心医院收治的94例子宫良性病变患者为研究对象,采用抽签法将患者分为试验组(n=47)和对照组(n=47)。试验组接受保留子宫韧带血管的子宫体大部切除术,对照组接受子宫体大部切除术。比较两组患者的手术时间、术中出血量、术后排气时间、下床活动时间、术后发热、尿潴留、手术切口甲级愈合情况;检测所有患者术前、术后6个月、术后12个月卵泡刺激素(FSH)、黄体生成素(LH)及雌二醇水平。结果试验组患者术中出血量、手术时间、术后排气时间、下床活动时间以及术后发热比例、手术切口甲级愈合情况比较,差异均无统计学意义(P>0.05);随着术后时间的延长两组患者FSH水平逐渐升高,但试验组升高的幅度较对照组小[(5.6±1.3)U/L、(5.4±1.8)U/L、(6.7±2.2)U/L比(5.4±1.8)U/L、(7.3±1.9)U/L、(10.3±3.2)U/L],两组患者血清FSH水平在组间、组间·时间点交互作用比较,差异有统计学意义(P<0.05),时间点比较差异无统计学意义(P>0.05);LH水平在组间、时间点以及组间·时间点交互作用比较差异无统计学意义(P>0.05);术后两组患者雌二醇水平均降低,但试验组降低的幅度较小[(325±15)pg/L、(315±19)pg/L、(289±12)pg/L比(327±18)pg/L、(224±21)pg/L、(232±14)pg/L],两组患者在组间、时间点以及组间·时间点交互作用比较差异有统计学意义(P<0.05)。结论保留子宫韧带血管的子宫体大部切除术治疗子宫良性疾病的效果与子宫体大部切除术相似,不增加不良反应,且对血清FSH以及雌二醇的水平的影响较小。Objective To study the clinical effect of the treatment of benign uterine disease by large partial excision of the uterine with the reservation of the uterine ligament. Methods A total of 94 cases of benign uterine lesions in Anshan Central Hospital from Jan. 2013 to Oct. 2014 were divided into a trial group and a control group,47 cases in each group. The trial group received large partial excision of uterine body with the reservation of the uterine ligament,and the control group received subtotal uterine resection. The operative time,intraoperative blood loss,postoperative exhaust time,ambulation time,postoperative fever,urinary retention and grade A incision healing of the two groups were compared; follicle-stimulating hormone（ FSH）,luteinizing hormone（ LH） and estradiol levels of all patients were collected before surgery,six months after surgery and 1 year after surgery. Results There were no differences in intraoperative blood loss,operative time,postoperative exhaust time,ambulation time,the number of cases of postoperative fever and grade A surgical incision healing between the two groups（ P〉0. 05）. The level of FSH in the two groups increased gradually after surgery,but FSH of the trial group was lower than the control group[（ 5. 6 ± 1. 3） U / L,（ 5. 4 ± 1. 8） U / L,（ 6. 7 ± 2. 2） U / L vs（ 5. 4 ± 1. 8） U / L,（ 7. 3 ± 1. 9） U/L,（ 10. 3 ± 3. 2） U/L]; the level of serum FSH between groups,groups·different time points had statistically significant difference（ P〈0. 05）,and the difference was not statistically significant between different time points（ P〉0. 05）. There were no difference in the level of LH between groups,time points and groups·time points（ P〉0. 05）. Estradiol levels were decreased in both groups after operation,but the reduction of the trial group was lower than that of the control group[（ 325 ± 15） pg / L,（ 315 ± 19） pg / L,（ 289 ± 12） pg / L vs（ 327 ± 18） pg / L,（ 224 ± 21） pg / L,（ 232 ± 14） pg / L]

关 键 词：子宫体大部切除术 子宫动脉上行支 临床疗效 

分 类 号：R713[医药卫生—妇产科学]