氨甲环酸在腰椎手术中应用的研究进展  

Research progress in the application of Tranexamic Acid in the lumbar vertebra surgery

作　　者：方浩[1] 滕勇[2] 陈建常[2] 

机构地区：[1]新疆医科大学研究生院,新疆乌鲁木齐830000 [2]新疆军区总医院骨科中心脊柱外科,新疆乌鲁木齐830000

出　　处：《中国医药导报》2017年第3期31-34,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(31360229)

摘　　要：腰椎手术显露过程中因切口深长、术中需要剥离的椎旁肌较多、手术时间长等因素,出血量通常较多,患者经常需要反复大量输血来确保生命体征的平稳。因此,临床常应用各种方法减少出血,如术中严格止血、缩短手术时间、术中应用抗纤维蛋白溶解药等。其中,抗纤维蛋白溶解药氨甲环酸的作用日显突出。它既可以减少患者出血量和住院费用,又未增加因患者术后卧床导致的静脉血栓等相关并发症。现就以氨甲环酸在腰椎手术中应用效果的相关研究进行综述。Exposing the lumbar vertebra surgery incision profound, need to peel off a lot of paravertebral muscle, long operative time, often lost a lot of blood, the patient often need a large amount of blood transfusion to ensure stable vital signs. Therefore, the clinical commonly use of a variety of methods to reduce bleeding, such as strict hemostasis during operation, shorten the operation time, the application of anti fibrin dissolve drugs. The anti fibrin dissolve medicine Tranexamic Acid has become an increasingly important role. On the one hand can reduce the bleeding and hospitaliza- tion expenses, on the other hand the incidence of postoperative venous thrombosis was not increased. This article sum- marizes the research progress of application of Tranexamic Acid in the lumbar vertebra operation.

关 键 词：氨甲环酸 腰椎手术 用药方式 用药剂量 

分 类 号：R681.5[医药卫生—骨科学]