STOP-Bang问卷及Epworth嗜睡评分预测OSAHS及与睡眠相关性研究  

The value of STOP-Bang questionnaire and Epworth sleepiness scale in diagnosis of obstructive sleep apnea-hyponea syndrome and their correlation with sleep

作　　者：尤青海[1] 牛成成[2] 贾丹[1] 蒋利娟[1] 刘雪婷[1] 朱钟鸣[1] 

机构地区：[1]安徽医科大学第一附属医院呼吸内科,安徽合肥230022 [2]安徽医科大学第一附属医院消毒供应中心,安徽合肥230022

出　　处：《临床肺科杂志》2017年第4期638-640,644,共4页Journal of Clinical Pulmonary Medicine

基　　金：国家临床重点专科建设项目基金(No2012·649)

摘　　要：目的探讨STOP-Bang问卷(SBQ)和Epworth嗜睡评分(ESS)在阻塞性睡眠呼吸暂停低通气综合征(OSAHS)诊断和评估睡眠质量中的价值。方法以51名鼾症患者为研究对象,行整夜多导睡眠监测前接受SBQ和ESS评估。结果 (1)单纯鼾症组与OSAHS组SBQ、ESS,非快动眼睡眠(Ⅰ期、Ⅱ期、Ⅲ+Ⅳ期)及快动眼睡眠(REM)、觉醒次数和微觉醒指数比较差异显著(P<0.05)。(2)SBQ≥3分筛查OSAHS灵敏度、特异度分别为89.50%、30.80%;ESS≥9分筛查OSAHS灵敏度、特异度分别为78.90%、69.20%;SBQ≥3与ESS≥9筛查OSAHS的差异有统计学意义(χ~2=7.513,P=0.006)。(3)SBQ与呼吸暂停/低通气指数(AHI)、Ⅱ期睡眠、觉醒次数、微觉醒指数正相关(P<0.05),与Ⅲ+Ⅳ期睡眠(%)和REM睡眠(%)负相关(P<0.05)。ESS与AHI、Ⅰ期睡眠、Ⅱ期睡眠、觉醒次数、微觉醒指数正相关(P<0.05),与Ⅲ+Ⅳ期睡眠(%)和REM睡眠(%)负相关(P<0.05)。结论 SBQ与ESS均能预测OSAHS、评估OSAHS睡眠质量,两者联合使用优于单一量表。Objective To explore the value of STOP-Bang questionnaire （SBQ） and Epworth sleepiness scale （ESS） in diagnosis of obstructive sleep apnea-hyponea syndrome （OSAHS） and the correlation with the quality of sleep. Methods 51 patients with snoring diseases were enrolled in the study. Before overnight polysomnography monitoring, SBQ and ESS were filled and analyzed. Results ① Between the primary snoring group and the OSAHS group, there were significantly differences in SBQ, ESS, non-rapid eye movement sleep （stage Ⅰ,Ⅱ,Ⅲ＋Ⅳ ） and rapid eye movement （REM） sleep, the number of awakening and microarousal index （ P 〈 0. 05 ）. ② The sensitivity and specificity of SBQ （ ≥3 ） to predict OSAHS were 89.50% and 30. 80%, and the sensitivity and specificity of ESS （≥9） screening for OSAHS were 78. 90% and 69. 20%. There was significant difference between SBQ （≥3） and ESS （ ≥9 ） for predicting OSAHS （c^2 = 7.513, P = 0. 006）. ③ There was positive correlation between SBQ and apnea/hypopnea index （AHI） , stage Ⅱ sleep, the number of awakening and microarousal index （ P 〈 0.05 ）, re- spectively, and negative correlation between SBQ and stage m ＋ stage IV sleep, REM sleep （ P 〈 0. 05 ）. There was positive correlation between ESS and AHI, stage I sleep, stage Ⅲ sleep, the number of awakening and microarousal index （ P 〈 0. 05）, and negative correlation between ESS and stage Ⅲ＋ stage IV sleep, REM sleep （ P 〈 0. 05 ）. Conclusion Both SBQ and ESS can predict OSAHS and assess sleep quality of OSAHS. The combination of SBQ and ESS may be superior to a single scale in the process.

关 键 词：STOP-Bang问卷 Epworth嗜睡评分 阻塞性睡眠呼吸暂停低通气综合征 评估 睡眠 

分 类 号：R56[医药卫生—呼吸系统]