血液灌流对血液透析患者睡眠障碍的疗效观察  

Observation on the curative effect of hemoperfusion on sleep disorders in hemodialysis patients

作　　者：张以勤[1] 沈志清[1] 叶婧[1] 周丽娜[1] 王玉新[1] 

机构地区：[1]厦门市第二医院肾内科,福建厦门361021

出　　处：《中国现代医生》2017年第2期76-78,共3页China Modern Doctor

摘　　要：目的观察血液灌流对维持性血液透析患者睡眠障碍的疗效。方法选择2014年1~6月我科维持性血液透析伴有睡眠障碍患者40例,加用血液灌流治疗,每周1次,治疗3个月。采用自身对照的方法,观察血液灌流前后患者睡眠质量评分(匹兹堡睡眠质量指数量表,PSQI)、血红蛋白、血小板、钙、磷、甲状旁腺激素(i PTH)、β2-微球蛋白水平的变化。结果血液灌流治疗后患者睡眠质量明显改善。除催眠药物外,PSQI各因子及总分明显降低(P<0.05)。血清磷、甲状旁腺激素(i PTH)、β2-微球蛋白水平也较治疗前下降(P<0.01)。结论血液灌流可改善透析患者的睡眠质量,提高血透患者的生活质量。Objective To observe the curative effect of hemoperfusion on sleep disorders in maintenance hemodialysis patients. Methods A total of 40 patients with maintenance hemodialysis accompanied with sleep disorders who were ad- mitted to our department from January to June 2014 were treated with hemoperfusion therapy once a week for. 3 months. Changes of sleep quality score（PSQI）, hemoglobin, platelet, calcium, phosphorus, parathyroid hormone （iPTH） and β2- microglobulin before and after hemoperfusion were observed by self-control method. Results The quality of sleep was significantly improved after hemoperfusion. In addition to hypnotic drugs, PSQI factors and total score were significantly lower（P〈0.05）. The levels of serum phosphorus, parathyroid hormone（iPTH） and β2-microglobulin were lower than those before treatment（P〈0.01）. Conclusion Hemoperfusion can improve the quality of sleep and improve the quality of life of dialysis patients.

关 键 词：血液灌流 血液透析 睡眠障碍 匹兹堡睡眠质量指数量表 

分 类 号：R459.5[医药卫生—治疗学]