新疆维吾尔族寻常型银屑病伴发代谢相关性疾病分析  

Analyses on Metabolic-related Diseases in Patients with Psoriasis Vulgaris in Xinjiang Uygur

作　　者：蒋建华[1] 卜晓琳[1] 范娟[1] Jiang Jianhua Bu X iaolin Fan Juan(Gongli Hospital, Second Military Medical University, Shanghai 200135, China)

机构地区：[1]上海市浦东新区公利医院,上海200135

出　　处：《中国中西医结合皮肤性病学杂志》2017年第1期41-44,共4页Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine

基　　金：浦东新区卫生系统优秀青年医学人才培养计划(编号:PWRq2013-02)

摘　　要：目的分析新疆维吾尔族寻常型银屑病患者伴发代谢相关性疾病的情况。方法对2010年1月—2013年3月新疆维吾尔自治区人民医院皮肤科住院的106例维吾尔族寻常型银屑病患者伴发代谢相关性疾病的临床资料进行回顾性分析,并与300例同期健康体检者伴发代谢相关性疾病的情况作比较。结果新疆维吾尔族寻常型银屑病患者伴发高血压、Ⅱ型糖尿病、高尿酸血症、代谢综合症和肥胖的几率均高于健康对照组;银屑病组中男性患代谢综合症(22.22%)和高尿酸血症(30.00%)均高于女性患者(6.25%,6.25%,P<0.05)。对照组性别方面差异无统计学意义(P>0.05)。银屑病合并各种代谢相关性疾病与无代谢相关性疾病比较,在年龄方面差异有统计学意义,合并代谢性疾病的患者年龄更大。在病程、发病年龄和文化程度方面差异无统计学意义。在严重程度方面组间差异有统计学意义,且代谢相关性疾病的发生随着严重程度的增加而增加。同时合并有多种代谢相关性疾病的银屑病患者,合并的代谢相关性疾病数量越多,银屑病的严重程度越重。结论新疆维吾尔族寻常型银屑病患者常伴发高血压、Ⅱ型糖尿病、高尿酸血症、代谢综合征及肥胖等代谢相关性疾病。男性较女性患者更易伴发高代谢综合征和高尿酸血症,合并代谢性疾病的患者年龄更大,代谢相关性疾病的发生随着严重程度的增加而增加,合并的代谢相关性疾病数量越多,银屑病的严重程度越重。因此应重视银屑病患者健康宣教。Objective In order to study the prevalence of metabolic-related diseases in patients with psoriasis vulgaris in Xinjiang Uygur. Methods A total of 106 Xinjiang Uygur psoriasis vulgaris hospitalized patients with metabolic-related diseases in department of dermatology in the people＇s hospital of Xinjiang Uygur Autonomous Region from Jan. 2010 to Mar.2013 were studied, and compared with 300 age-matched healthy controls. Results The patients with psoriasis vulgaris in Xinjiang Uygur had a higher prevalence of hypertension（HT）, diabetes mellitus of Ⅱ（DM）, hyperuricemia（HUA）, fat and metabolic syndrome（MS, P0.05）. A higher prevalence of HUA and MS were found in male patients with psoriasis vulgaris in Xinjiang Uygur. There were significant differences in the age of psoriasis with various and none, and the metabolic-related diseases were older. There were no significant differences in the course of disease, age and educational level. There were significant differences between groups in PASI, and metabolic-related diseases increased with PASI. There were a variety of metabolic-related diseases in patients with psoriasis, the more number of metabolic-related diseases, the more severe of psoriasis. Conclusion Metabolic-related diseases are common in patients with psoriasis vulgaris in Xinjiang Uygur. Male patients with psoriasis vulgaris in Xinjiang Uyger has a higher prevalence of HUA and MS than the female patients. The patients of metabolic-related diseases are older than common psoriasis patients. Metabolic-related diseases are increased with PASI. It should pay more attention to health education of the patients with psoriasis.

关 键 词：寻常型银屑病 代谢相关性疾病 新疆维吾尔族 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]