老年男性高血压患者心血管疾病检出率与血压达标的相关性研究  

Correlation between prevalene of cardiovascular diseases and controlled hypertension in elderly male hypertensive patients

作　　者：王晓曦[1] 崔华[1] 蔡毅[1] 范利[1] WANG Xiao-xi CUI Hua CAI Yi et al(Department of Geriatric Cardiology, Chinese PLA General Hospital, Beij ing 100853, China)

机构地区：[1]解放军总医院南楼心血管内科,北京100853

出　　处：《中华老年心脑血管病杂志》2017年第3期236-240,共5页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的探讨血压全程管理良好的老年男性高血压患者心血管疾病检出率与血压达标情况的相关性。方法选择老年男性患者719例,其中正常血压组228例,血压达标组389例,血压不达标组102例。调查冠心病(包括不同类型的心绞痛和心肌梗死)、慢性心力衰竭、阵发性心房颤动和持续性心房颤动检出率与血压达标的相关性。结果血压达标组心绞痛、心肌梗死检出率明显高于正常血压组(48.8%vs 26.8%,P<0.01;16.2%vs 6.6%,P<0.01)。血压不达标组心绞痛、心肌梗死、阵发性心房颤动、持续性心房颤动检出率明显高于正常血压组(62.7%vs26.8%,P<0.01;12.7%vs 6.6%,P<0.01;11.8%vs 4.8%,P<0.05;8.8%vs 3.1%,P<0.05)。血压不达标患者冠心病(心绞痛和心肌梗死)发病风险较血压达标患者增高(OR=5.067 vs OR=3.561)。结论老年男性高血压患者,降压治疗及血糖、血脂、肥胖等危险因素的控制虽然能够降低心血管疾病检出率,但高血压的发生及理想血压的控制在心血管疾病的发生和发展中起到重要作用;年龄和伴随疾病等因素也影响患者的预后。Objective To study the correlation between the prevalence of cardiovascular diseases and controlled hypertension in elderly male hypertensive patients.Methods Seven hundred and nineteen male hypertensive patients were divided into normotensive group（n=228）,well-controlled hypertension group（n=389）and poorly-controlled hypertension group（n=102）.The correlation of the prevalence of coronary heart disease（CHD）,chronic heart failure,paroxysmal atrial fibrillation（AF）,persistent AF with controlled hypertension was analyzed.Results The prevalence of angina pectoris and myocardial infarction was significantly higher in well-controlled hypertension group than in normotensive group（48.8%vs 26.8%,P〈0.01;16.2% vs 6.6%,P〈0.01）.The prevalence of angina pectoris,myocardial infarction,paroxysmal AF,and persistent AF was significantly higher in well-controlled hypertension group than in poorly-controlled hypertension group（62.7%vs 26.8%,P〈0.01,12.7% vs 6.6%,P〈0.01;11.8% vs 4.8%,P〈0.05;8.8%vs 3.1%,P〈0.05）.The risk to develop CHD was significantly greater in well-controlled hypertension group than in poorly-controlled hypertension group（OR=5.067 vs OR=3.561）.Conclusion Although antihypertensionsion treatment and control of the risk factors,such as blood glucose,blood lipids,and obesity,can reduce the prevalence of cardiovascular diseases in elderly male hypertensive patients,effective control of hypertension still plays an important role in control of the occurrence and development of cardiovascular diseases.Age and other concomitant diseases can also affect the outcomes in hypertensive patients.

关 键 词：高血压 心血管疾病 冠心病 心力衰竭 心房颤动 发病率 性别因素 

分 类 号：R544.1[医药卫生—心血管疾病]