鲍曼不动杆菌医院感染溯源研究  

Tracing investigation of Acinetobacter baumannii infection in hospital

作　　者：汪洋[1] 崔明花[2] 吴晓松[3] 陈越英[3] 王嵬[3] 何仁伟[2] 褚宏亮[3] 谈智[3] 钱慧敏[3] 孔筱筱 徐燕[3] 

机构地区：[1]南京医科大学,江苏南京210029 [2]江苏省宿迁市疾病预防控制中心 [3]江苏省疾病预防控制中心

出　　处：《中国消毒学杂志》2017年第2期133-135,139,共4页Chinese Journal of Disinfection

基　　金：江苏省社会发展科技示范工程(BE2015714);全国医院消毒与感染控制监测项目(环境所[2015]55号)

摘　　要：目的追溯医院感染鲍曼不动杆菌的来源,进行医院感染源头控制。方法通过分离鉴定和分子分型技术,对江苏某医院ICU分离到的不动杆菌属进行溯源研究。结果从该医院ICU各种送检标本中分离出64株不动杆菌属,鉴定确认其中34株为鲍曼不动杆菌,分别来自感染患者5株、物体表面27株、医护人员手1株和空气标本1株。分离自患者痰液的菌株分型与其周边物体表面和医护人员手分离菌株一致。患者标本分离的5株鲍曼不动杆菌全部为多重耐药菌株。结论本研究通过分型溯源方式发现医院感染病原菌很多与其周围环境分离菌株具有同源性,说明有效控制环境污染有助于医院感染的防控。Objective To search for the sources of nosocomial infection caused by Acinetobacter baumannii and take source control measures. Methods Source tracing of Acinetobacter bacteria strains isolated from a ICU of a hospital in Jiangsu province by isolation,identification and molecular subtyping technology. Results 34 strains of Acinetobacter baumannii（ 5from patients,27 from variety of surfaces,1 from hands of a medical worker and 1 from air） were identified from 64 strains of Acinetobacter bacteria. Strains isolated from sputum of patients share the same PFGE pattern with the strains isolated from surfaces and hands of medical staffs. 5 patients strains were all multiple- drug resistant. Conclusion The homology of Acinetobacter baumannii between patients and the ICU environment was recognized by source tracing using molecular subtyping in this study. Effective control of environmental contamination was proved to be conducive to the prevention and control of nosocomial infection.

关 键 词：鲍曼不动杆菌 医院感染 分子分型 溯源研究 

分 类 号：R378[医药卫生—病原生物学]