北豆根药材粉末色泽与有效成分的相关性  

Correlation Between Color Traits of Menispermi Rhizoma Powder and Its Effective Components

作　　者：何婉婉[1] 张建逵[1] 李云静[1] 康廷国[1] 

机构地区：[1]辽宁中医药大学药学院,辽宁大连116600

出　　处：《中国实验方剂学杂志》2017年第5期57-62,共6页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家中医药管理局中医药行业科研专项(201407002);辽宁省中药原料质量检测体系建设项目

摘　　要：目的:研究北豆根药材粉末色泽与4种有效成分及总生物碱含量的相关性。方法:用色差计测量北豆根药材粉末ΔL*,Δa*,Δb*和ΔE*值,采用HPLC法对北豆根中青藤碱、蝙蝠葛苏林碱、蝙蝠葛碱以及粉防己碱4种成分进行含量测定,并用SPSS 15.0统计软件对数据进行相关性分析。结果:明度ΔL*,总色差ΔE*均与蝙蝠葛碱含量呈极显著的相关性(P<0.01);所有色泽指标与青藤碱、蝙蝠葛苏林碱、粉防己碱的含量均不具相关性;但色泽指标Δa*,Δb*,ΔE*与蝙蝠葛苏林碱和蝙蝠葛碱含量总和以及4种生物碱含量总和均存在显著正相关(P<0.05)。结论:北豆根粉末橙红色越深、总色差越大,蝙蝠葛苏林碱和蝙蝠葛碱含量总和越大,4种生物碱含量总和越大。Objective： To study the correlation between color trait of Menispermi Rhizoma powder and contents of total alkaloids. Method： The value of △L＊ , △a＊ , △b＊ and △E＊ of Menispermi Rhizoma powder were determined by the colorimeter, and the contents of four chemical components （sinomenine, daurisoline, dauricine and tetrandrine） were detected by HPLC, then the data were analyzed by SPSS 15.0 software to explore the correlation. Result： The brightness value of △L＊ , total chromatic aberration value of AE＊ and the content of dauricine showed significant correlation （P 〈 0.01） ; there was no significant correlation between all color indexes and contents of sinomenine, daurisoline and tetrandrine. However, color indexes of △a＊, △b＊, △E＊ had significant positive correlation with the total contents of daurisoline and dauricine and four kinds of alkaloids （P 〈 0.05）. Conclusion： The deeper orange red of Menispermi Rhizoma power and bigger total color difference, the greater total contents of daurisoline and dauricine and four kinds of alkaloids.

关 键 词：北豆根 色泽 有效成分 质量评价 相关性 

分 类 号：R284.1[医药卫生—中药学]