窒息复苏后4h内气管内吸引治疗新生儿胎粪吸入综合征的临床观察  

Clinical effect of endotracheal suction within 4 h after asphyxia resuscitation on meconium aspiration syndrome in neonates

作　　者：冯瑾[1] Feng Jin(Neonatal Department, The Second People＇s Hospital of Yulin, Yulin 537000, Chin)

机构地区：[1]广西玉林市第二人民医院新生儿科,玉林537000

出　　处：《广西医科大学学报》2017年第3期424-427,共4页Journal of Guangxi Medical University

摘　　要：目的:寻找减轻新生儿胎粪吸入综合征(MAS)病情的简易可行的临床治疗方法。方法:选取2011年8月至2016年5月玉林市第二人民医院新生儿科收治的MAS新生儿97例,将其随机分为观察组(49例)和对照组(48例)。观察组患儿在入院时先予气管内吸引后,再给予常规治疗;对照组患儿仅给予常规治疗。比较两组患儿的机械通气时间、氧疗时间、抗生素使用级别、抗生素使用时间、胸片病灶消退时间以及并发症发生情况。结果:两组患儿机械通气时间、氧疗时间、抗生素使用级别、抗生素使用时间、胸片病灶消退时间比较,差异均有统计学意义(均P<0.001)。观察组患儿持续性肺动脉高压(PPHN)发生率明显低于对照组,差异有统计学意义(P<0.05)。结论:新生儿MAS窒息复苏后4h内给予气管内吸引术可以有效减少机械通气时间、氧疗时间和抗生素使用时间,降低抗生素级别,促进胸片病灶消退,降低新生儿PPHN的发生率。Objective：To evaluate the clinical effect of endotracheal suction within 4 h after asphyxia resusci- tation on meconium aspiration syndrome （MAS） in neonates. Methods：From August 2011 to May 2016, 97 neonates with MAS treated in our hospital were selected and randomly divided into an observation group （49 cases） and a control group （48 cases）. The children in the observation group received endotracheal suc- tion followed by conventional treatment, while those in the control group only received conventional treat- ment. The mechanical ventilation time, duration of oxygen therapy, antibiotics level, using time of antibi- otics and the incidence of complications were compared between the two groups. Results： There were statis- tical differences in the mechanical ventilation time, duration of oxygen therapy, antibiotics level, the using time of antibiotics and fading time of chest lesions between the two groups （ P 〈0. 001）. The incidence of persistent pulmonary hypertension of newborn （PPHN） in the observation group was significantly lower than that in the control group （ P 〈0.001）. Conclusion.Endotracheal suction within 4 h after asphyxia re- suscitation could effectively reduce mechanical ventilation and oxygen therapy duration, antibiotic user an-tibiotic level and the incidence of PPHN as well as promote chest lesions subsided in neonates with MAS.

关 键 词：新生儿胎粪吸入综合征 气管内吸引术 窒息复苏 

分 类 号：R722.12[医药卫生—儿科]