比较超声引导下局部注射32P胶体及曲安奈德与无水乙醇治疗甲状腺囊肿的疗效  

Comparison of Efficacy of 32p Colloid Combined with Triamcinolone Acetonide and Ethanol Alone in Treatment of Thyroid Cyst

作　　者：曾昭辉[1] 滕强丰[2] 殷跃[1] 

机构地区：[1]湖南省人民医院核医学科,湖南长沙410005 [2]广西医科大学第一附属医院核医学科,广西南宁530021

出　　处：《医学临床研究》2017年第2期306-308,共3页Journal of Clinical Research

摘　　要：【目的】比较超声引导下局部注射32P胶体及曲安奈德与无水乙醇治疗甲状腺囊肿临床疗效。【方法】选取2010年2月至2014年6月广西医科大学第一附属医院收治的甲状腺囊肿患者372例,随机分为观察组和对照组,每组各186例。对照组在超声引导下穿刺注射无水乙醇,观察组在超声引导下注射32P胶体及曲安奈德,比较两组患者临床疗效,并于术后1年进行随访,记录两组患者复发情况。【结果】观察组：治愈158例（84.9%）、有效23例（12.4%）、无效5例（2.7%）,有效率为97.3%（181/186）;对照组：治愈139例（74.7%）、有效38例（20.4%）、无效9例（4.9%）,有效率为95.1%（177/186）。观察组有效率显著高于对照组,经秩和检验差异有统计学意义（P=0.014）。术后随访一年,两组治愈及有效患者均无复发病例。【结论】超声引导下局部注射32P胶体及曲安奈德治疗甲状腺囊肿,具有操作简便、安全、治疗效果好等优点,且创伤小、患者易于接受,可作为甲状腺囊肿的常规治疗方法。【Objective】To compare the clinical efficacy of local injection of 32P colloid combined with triamcinolone acetonide and the therapy of absolute ethanol in the treatment of thyroid cyst.【Methods】 From February 2010 to June 2014, 372 patients with thyroid cyst in our hospital were randomly divided into observation group and control group, each group had a total of 186 cases.The control group underwent percutaneous ethanol injection under ultrasound guided, the observation group underwent injection of triamcinolone acetonide and 32P colloid under ultrasound guided. The clinical efficacy of the two groups were compared, and the patients were followed up for at least 1 year after operation. The recurrence of the two groups were recorded.【Results】In the observation group： 158 cases （84.9%） were cured, effective in 23 cases （12.4%）, ineffective in 5 cases （2.7%）, the effective rate was 97.3% （181/186）; in the control group： i139 cases were cured （74.7%）, effective in 38 cases （20.4%）, invalid in 9 cases （4.9%）, the effective rate was 95.1%（177/186）.The effective rate of the observation group was significantly higher than that of the control group, and the difference was statistically significant （P=0.014）. All patients were followed up for one year. There were no recurrence cases in the two groups.【Conclusion】The therapy of injection of 32P colloid and triamcinolone acetonide under Ultrasound guided for the treatment of thyroid cyst has the advantages of simple operation, safety with good treatment effect to be easily accepted by patients with small wound. It can be used as a routine treatment for thyroid cyst.

关 键 词：磷放射性同位素/治疗应用 胶剂 甲状腺肿/药物疗法 甲状腺肿/超声检查 曲安奈德/治疗应用 乙醇/治疗应用 

分 类 号：R581.3[医药卫生—内分泌]