某地区小儿血流感染病原菌分布及耐药性分析  

Distribution and drug resistance of pathogenic bacteria in children with blood stream infection in some area

作　　者：梁亮[1] 叶余辉[1] 庞兴翠[1] 

机构地区：[1]北海市人民医院检验科,广西536000

出　　处：《国际检验医学杂志》2017年第5期604-605,608,共3页International Journal of Laboratory Medicine

摘　　要：目的探讨北海地区小儿患者血流感染(BSI)病原菌分布及其耐药性。方法回顾性分析2013年1月至2016年6月发生BSI的小儿患者临床资料。结果本地区95.3%的小儿BSI为社区获得性感染。革兰阳性球菌与阴性杆菌所占比例分别为53.5%、46.5%。万古霉素、利奈唑胺对阳性球菌耐药率均为0.0%;哌拉西林、哌拉西林/他唑巴坦、头孢吡肟、美罗培南对革兰阴性杆菌的耐药率分别9.3%、0.0%、9.1%、5.0%。结论革兰阳性球菌与阴性杆菌感染比例基本一致。万古霉素、利奈唑胺可作阳性球菌BSI的经验用药;哌拉西林、哌拉西林/他唑巴坦、头孢吡肟、美罗培南可作革兰阴性杆菌BSI的经验用药。Objective To investigate the distribution and drug resistance of pathogenic bacteria in children with blood stream infection（BSI）in Beihai area.Methods The clinical data of children with blood stream infection from January 2013 to June 2016 were retrospectively analyzed.Results 95.3% of BSI children patients were community acquired infection.The proportions of Gram-positive cocci and Gram-negative bacilli were 53.5%and 46.5%respectively.The resistance rates of vancomycin and linezolid to Grampositive cocci all were 0%;which of piperacillin,piperacillin/tazobactam,cefepime and meropenem to Gram-negative bacilli were9.3%,0.0%,9.1%and 5.0%respectively.Conclusion The proportion of Gram-positive cocci and Gram-negative bacilli is basically consistent.Vancomycin and linezolid can be used as the empiric medication of Gram-positive cocci BSI;piperacillin,piperacillin/tazobactam,cefepime and meropenem and can be used as the empiric medication of Gram-negative bacilli BSI.

关 键 词：血流感染 革兰阳性球菌 革兰阴性杆菌 耐药率 

分 类 号：R446.5[医药卫生—诊断学] R725.1[医药卫生—临床医学]